Single-Cell RNA-Seq (scRNA-Seq) Bioinformatics Jobs

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
See All Open Jobs
Grail
Permanent
June 26, 2026

Senior Data Scientist # 4630

$156K - $187K
Menlo Park, CA
Hybrid

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

GRAIL is seeking a Senior Data Scientist to join the Machine Learning team within the Computational Biology and Machine Learning (CBML) group. In this role, you will work at the intersection of machine learning, genomics, and clinical science to advance early cancer detection. You will collaborate closely with scientists, engineers, and clinicians to identify novel biological signals, improve classification performance, and develop innovative approaches for cancer detection and categorization using GRAIL’s rich sequencing datasets.

This is a highly impactful role where you will apply state-of-the-art machine learning techniques—including modern AI approaches—to real-world clinical challenges. Your work will directly contribute to scientific discoveries, peer-reviewed publications, and the development of transformative products for early cancer detection.

This is a hybrid role based in Menlo Park, CA (moving to Sunnyvale, CA in Fall 2026). Our current flexible work arrangement policy requires that a minimum of 40%, or 16 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 40% requirement for the site.

Responsibilities:

  • Envision, design, and lead projects to evaluate and improve machine learning classifier performance for cancer detection
  • Collaborate cross-functionally with scientists, engineers, and clinicians to plan, execute, and interpret experiments
  • Develop high-quality, reproducible, and scalable software aligned with sound engineering principles
  • Apply best practices in machine learning and statistics to generate robust, interpretable, and reliable results
  • Analyze large-scale sequencing and genomics datasets to extract meaningful biological insights
  • Contribute to the development and evaluation of novel machine learning methods, including deep learning approaches
  • Communicate findings and present updates regularly in technical and cross-functional forums
  • Contribute to scientific publications, internal tools, and production systems

These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.

Required Qualifications

Required Qualifications

  • Ph.D. in Bioinformatics, Computational Biology, Computer Science, Statistics, Machine Learning, or a related field with 2+ years of relevant experience, OR
    M.S. with 4+ years of relevant experience, OR
    B.S. with 6+ years of relevant experience, or equivalent practical experience
  • 2+ years of experience applying machine learning or statistical modeling in a research or production environment
  • Strong expertise in data analysis using Python or R
  • Deep understanding of modern machine learning and statistical methods
  • Experience developing reproducible, well-structured code in a collaborative environment
  • Strong written and verbal communication skills

Preferred Qualifications:

  • Experience with modern AI techniques, including deep learning and/or large language model (LLM) training or adaptation
  • Experience working with sequencing or genomics data and deriving biological insights
  • Track record of scientific contributions (e.g., publications, tools, datasets, patents, or conference presentations)
  • Experience with system-level programming languages (e.g., Go, Java, C, C++)
  • Familiarity with version control (e.g., Git) and reproducible research practices in Linux environments
  • Demonstrated ability to independently drive projects while collaborating effectively across teams
  • Interest in translating research innovations into production-ready systems

The expected, full-time, annual base pay scale for this position is 156K - $187K.  Actual base pay will consider skills, experience, and location.

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at rc@grailbio.com if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!

GenBio AI
Permanent
June 26, 2026

Research Scientist, Applied Science

TBD
Palo Alto, CA
Onsite

GenBio AI develops multiscale foundation models to decode and simulate human biology. Our team is accelerating towards an ambitious future where scientists can unlock humanity's biggest challenges in drug discovery, healthcare, and fundamental research with AIDO (AI-Driven Digital Organism): a unified framework for predicting, simulating, and programming biology across all scales. The foundation of this vision begins today as we engineer the virtual cell to model and simulate the fundamental unit of life.

This vision has brought together a talent-dense group of product-minded researchers and engineers dedicated to bringing it to reality. Our team prides itself on our strong engineering culture and highly interdisciplinary and collaborative approach. We are based in Palo Alto, with satellite offices in Paris and Abu Dhabi.

This role combines research in AI for structural biology with the application of our models to real-world scientific challenges. The successful candidate will contribute to model development, lead computational discovery efforts in collaboration with external partners, and help translate research advances into impactful outcomes. Depending on business needs, time may be split between partner-facing scientific projects and internal research initiatives.

Job Requirements

  • PhD (or evidence of equivalent level of expertise) in Computer Science, Artificial Intelligence, Computational Biology,  or a related technical field.  
  • Proven track record in research and innovation demonstrated through contributions in top-tier AI/ML (e.g., NeurIPS, ICML, CVPR, ECCV, ICCV, ICLR) and/or core biology (e.g., Nature, Science, or Cell) journals and conferences.  
  • Experience in translating machine learning research into real-world scientific impact through collaborations with academic, biotechnology, or pharmaceutical partners.
  • Experience designing, executing, or supporting computational discovery campaigns in protein engineering, antibody discovery, binder design, or related therapeutic discovery efforts.
  • Experience working closely with experimental scientists and using experimental results to guide decisions.
  • Prior experience working on AI for structural biology or drug discovery in either an academic or industry setting.
  • Motivated and self-driven with the ability to operate with partial and incomplete descriptions of high-level objectives (as is typical in a start-up environment).  
  • Evidence of familiarity and utilization of software engineering best practices (version controlling, documentation, etc), and open-source contributions, especially if used by others.  

Preferred Qualifications

  • 3+ years of post-PhD experience in an industry or postdoc role
  • Prior experience working at either a start-up or top research industry labs (e.g., OpenAI, FAIR, Deepmind, Google Research).
  • Experience in biological structure prediction algorithms such as Alphafold2 & 3, RosettaFold.
  • Experience in generative modeling for biological structures and sequences
  • Experience leading scientific collaborations or serving as a technical point of contact for external research partners.
  • Deep knowledge of diffusion models, flow matching, and protein sequence models

BillionToOne
Permanent
June 26, 2026

Quality Engineer, Prenatal

$123,262 - $133,981
Union City, CA
Onsite

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for a Quality Engineer, Prenatal Lab Operations with a strong background in the LDT environment and expertise in lab practices, bioinformatics, report automation, assays, and reagents. Additionally, you will possess a deep understanding of quality tools and practices to ensure the highest standards of our products and services. In this role you will be responsible for identifying, developing, and executing process improvements and will work closely with cross-functional stakeholders across BillionToOne (e.g. Lab Operations, Bioinformatics, Process Engineering, Software Engineering, R&D). You will lead the analysis of data to identify improvement initiatives and will execute those process improvements from initial requirements gathering to go-live and further continuous improvement. This role is an onsite position in Union City, CA and reports to the Quality Manager, Prenatal.

Responsibilities:

  • Collaborate with cross-functional teams, including laboratory operations, customer support, bioinformatics, software engineering, and assay development, to monitor and maintain operations, investigate issues, perform changes, and identify improvement.
  • Partner with and drive occurrence management activities with cross-functional leads, including Nonconformances, CAPAs, Deviations, and Complaints.
  • Develop or improve, implement, maintain, and monitor quality assurance programs and systems to ensure compliance with regulatory requirements (CLIA, CAP, NYSDOH, etc.).
  • Provide hands-on training, partnership, and mentorship to laboratory staff, quality peers, and cross-functional personnel on quality processes, procedures, tools, and best practices as applicable.
  • Partner with authors and provide quality review of technical requirements, design specifications, risk management, validation and verification protocols and reports, and other quality records as a part of laboratory operations, change control, and new product development.
  • Support the internal audit program and other continuous improvement processes.
  • Track quality KPIs, analyze trends, and generate metrics reports or presentations with discussion and conclusions.
  • Contribute to additional QMS functions as needed, including supplier quality.
  • Maintain compliance with applicable FDA, CLIA, CAP, and ISO requirements and related guidances.

Qualifications:

  • Bachelor's degree in a scientific or technical field.
  • Minimum of 5 years of experience within the LDT industry and familiarity with relevant regulations and guidelines, such as CLIA, CAP, and state-specific requirements for LDTs. Equivalent or additional experience in medical devices under FDA and ISO.
  • Passion for mentoring early-career quality peers and championing quality culture cross-functionally.
  • Expertise in quality tools and practices, quality management systems, and continuous improvement methodologies.
  • Comfortable navigating ambiguity and shifting priorities in a high-growth environment using proactive and creative thinking to make meaningful contributions.
  • Strong project management skills with a track record of driving cross-functional initiatives to completion.
  • Ability to drive results to established timelines, communicate effectively both in writing and verbally, and work independently and cross-functionally to implement systems and processes.

Nice-To-Haves:

  • Expertise in Quality Improvement such as Lean, Six Sigma, and Root Cause Analysis.
  • Expertise in Product Quality such as Design Control, Risk Management, and Usability.
  • Experience in Software Quality and related practices such as Agile/Scrum.
  • Experience in practical teaching of topics relevant to this role and industry.
  • Knowledge of ISO 13485, ISO 14971, ISO 15189, IEC 62304, IEC 62366, and ISO/IEC 42001.
  • Familiarity with electronic quality management systems (e.g., Arena, Medialab).
  • Familiarity or expertise with data visualization tools (e.g., Tableau).
  • Quality or Project Management certifications.

Benefits And Perks:

  • Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
  • Open, transparent culture that includes weekly Town Hall meetings
  • The ability to indirectly or directly change the lives of hundreds of thousands patients
  • Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
  • Extremely generous Family Bonding Leave for eligible employees (16 weeks, paid at 100%)
  • Supplemental fertility benefits coverage
  • Retirement savings program including a 4% Company match
  • Increase paid time off with increased tenure
  • Latest and greatest hardware (laptop, lab equipment, facilities)
  • Free daily on-site lunches provided from top eateries
  • A variety of perks on campus (state of the art gym, restaurant)
  • Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $172,379 per year, including a base pay range of $123,262 - $133,981 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

For more information about how we protect your information, we encourage you to review our Privacy Policy.

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.Unity Confirm™ enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne’s Fetal Cell Capture™ Technology.Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com

10x Genomics
Permanent
June 22, 2026

Clinical Laboratory Scientist, (Technical Supervisor)

$158,400 - $214,400
Pleasanton, California
Onsite

10x Genomics is establishing a diagnostics effort to translate its leading single-cell and spatial genomics technologies into impactful clinical applications. This position performs and provides scientific and technical oversight for high-complexity next-generation sequencing (NGS) assays within a CLIA-certified laboratory.

The Technical Supervisor serves as the subject matter expert for assay validation, quality systems, and troubleshooting, partnering closely with laboratory leadership to maintain operational excellence and continuous improvement.

Role Overview

  • Position: Clinical Laboratory Scientist / Technical Supervisor (NGS Diagnostics)
  • Location: Onsite
  • Base Compensation Range: $158,400 - $214,400 / year

This role is accountable for ensuring the operational execution, analytical validity, performance, and regulatory compliance of all clinical NGS testing.

Responsibilities

Technical Oversight & Operations

  • Provide operational execution and technical oversight of high-complexity NGS assays, ensuring analytical accuracy and reliability of test results.
  • Serve as the primary technical resource for troubleshooting complex assay, instrumentation, and bioinformatics issues.
  • Evaluate and approve changes to assays, workflows, instrumentation, and software, including revalidation as required.
  • Oversee proficiency testing, method comparisons, and ongoing assay performance monitoring.
  • Provide technical training and competency assessments for laboratory personnel.

Quality Assurance & Compliance

  • Validate and implement NGS assays in accordance with CLIA, CAP, and applicable regulatory standards.
  • Establish and monitor quality control (QC) and quality assurance (QA) programs, including the review of performance metrics, trends, and corrective actions.
  • Author, review, and approve technical documentation, including standard operating procedures (SOPs), validation protocols/reports, and test methods.
  • Ensure compliance with all regulatory requirements and support internal and external audits and inspections.

Cross-Functional Collaboration

  • Partner with cross-functional teams (Bioinformatics, R&D, Quality, and Operations) to support assay optimization and innovation.
  • Stay current with emerging technologies, regulatory updates, and best practices in NGS and molecular diagnostics.

Required Qualifications

  • Licensure: Active California Clinical Laboratory Scientist (CLS) license meeting CLIA requirements for Technical Supervisor of high-complexity testing.
  • CLIA Alignment: Meets CLIA Technical Supervisor qualifications under 42 CFR 493.1449, including appropriate education, training, and experience.
  • Education: Bachelor’s degree in chemical, biological, physical, clinical laboratory science, or a related field.
  • Experience: Minimum of 4–6 years of experience in a CLIA-certified molecular diagnostics laboratory.
  • Technical Expertise: Significant experience in NGS assay validation, implementation, and operation, including library preparation, sequencing platforms, and bioinformatics analysis pipelines.
  • Regulatory Knowledge: Strong knowledge of CLIA, CAP, NYS, and other regulatory frameworks governing high-complexity testing.

Preferred Attributes

  • Prior experience serving specifically as a CLIA Technical Supervisor.
  • Experience working within a startup or high-growth laboratory environment.
  • A strong background in medical or oncology diagnostics.
  • Excellent analytical, problem-solving, and decision-making skills.
  • Strong written and verbal communication skills, with the ability to convey complex technical concepts clearly.

Compensation & Total Rewards

The hiring range for this position is $158,400 to $214,400 USD per year, depending on unique skills, qualifications, and experience.

In addition to base pay, 10x Genomics offers a comprehensive total rewards package:

  • Equity grants
  • Comprehensive health benefits
  • Retirement benefit programs
  • Annual bonus program or sales incentive program

Equal Opportunity & Security Protections

Candidate Security Notice: Please be aware of recruitment scams impersonating 10x Genomics. All official recruiting communication will come exclusively from email addresses ending in @10xgenomics.com. Candidates are encouraged to apply directly via Careers.10xgenomics.com. The company will never request payment or sensitive personal financial information during the recruiting process.

10x Genomics is an Equal Opportunity Employer. Individuals seeking employment are considered without regard to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, sexual orientation, or any other characteristic protected by applicable law.

Deep Genomics
Permanent
June 22, 2026

Senior Research Scientist, Machine Learning (BioFM)

TBD
Toronto, Ontario or Cambridge, MA
Onsite

Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of RNA biology to identify novel drug targets, mechanisms, and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team is revolutionizing how new medicines are created.  

Role Overview

  • Position: Senior / Staff Machine Learning Scientist
  • Locations: Toronto, ON or Cambridge, MA (Kendall Square)
  • Core Focus: Building Biological Foundation Models (BioFMs) from first principles

We are seeking an exceptional and creative Senior/Staff Machine Learning Scientist to lead and innovate within our core AI research team. Rather than just applying out-of-the-box ML to biological datasets, you will pioneer novel deep learning architectures and pre-training paradigms that learn the fundamental language of the genome and cellular biology. This is a unique opportunity for a first-principles thinker excited to bridge advanced ML with genome biology to solve frontier problems in human health.

Key Responsibilities

  • BioFM Architecture & Training: Lead the creative research, architecture design, and training of Biological Foundation Models (BioFMs) using massive-scale genomic, transcriptomic, and single-cell datasets.
  • Integrate Biological Priors: Collaborate closely with computational biologists and drug developers to embed deep biological priors directly into model architectures and training objectives.
  • Scale & Validate: Rigorously implement, train, debug, and evaluate large-scale models in PyTorch to demonstrate scientific validity and drive progress on genetic medicines.
  • Leadership & Mentorship: Mentor junior scientists and engineers, fostering a culture of technical excellence through high-quality code reviews and research guidance.
  • Scientific Community Engagement: Share findings through internal presentations and contribute to the broader scientific community via publications in top-tier venues.

Qualifications

Basic Qualifications

  • Education: PhD (or equivalent level of expertise) with a distinguished research focus in Computational Biology, Machine Learning, Computer Science, or a related quantitative field.
  • Foundation Modeling: Deep understanding of modern deep learning and the creative building of foundation models (e.g., CNNs, Transformers, and State-Space Models) tailored for biological sequence data.
  • Scale & Execution: A proven track record of building and scaling AI models for complex biological datasets (e.g., single-cell genomics, DNA/RNA sequences) from initial conception to production.
  • Engineering Rigor: Proven ability to implement, train, and debug highly performant deep learning models using frameworks like PyTorch, alongside a strong grasp of the engineering challenges associated with data at scale.
  • Communication: Excellent communication skills, capable of discussing complex ideas seamlessly with both ML engineers and biological domain experts.

Preferred Qualifications

  • Publication Track Record: Impactful research demonstrated through first-author publications in high-impact scientific journals (Nature, Science, Cell) or top-tier ML/CompBio conferences (NeurIPS, ICML, ICLR, ISMB, RECOMB).
  • Industry Experience: 2+ years of relevant post-graduate experience at a leading industrial R&D lab or a highly competitive academic environment building genomics AI.
  • Leadership: Prior experience technically leading projects or formally mentoring junior researchers and engineers.
  • Infrastructure & Open Source: Proficiency with cloud computing platforms (e.g., GCP) for large-scale training, and a history of contributions to open-source ML or computational biology projects.

What We Offer

  • Culture & Innovation: A collaborative and innovative environment at the frontier of computational biology, machine learning, and drug discovery.
  • Compensation: Highly competitive compensation, including meaningful stock ownership.
  • Comprehensive Benefits: Health, vision, and dental coverage for employees and families, plus an employee and family assistance program.
  • Flexible Work Environment: Flexible hours, extended long weekends, holiday shutdown, and unlimited personal days.
  • Family Support: Maternity and parental leave top-up coverage, alongside new parent paid time off.
  • Growth & Location: Dedicated learning and development budgets. Facilities are located in the machine learning hub of Toronto and the biotechnology epicenter of Kendall Square in Cambridge, MA.

Deep Genomics
Permanent
June 22, 2026

Senior Research Engineer, Machine Learning

TBD
Toronto, Ontario or Cambridge, MA
Onsite

Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of RNA biology to identify novel drug targets, mechanisms, and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team is revolutionizing how new medicines are created.  

Role Overview

  • Position: Machine Learning Research Engineer
  • Locations: Toronto, ON or Cambridge, MA (Kendall Square)
  • Environment: Collaborative and multidisciplinary, blending computational and wet-lab sciences

We are looking for a research engineer who bridges the gap between fast-paced, experimental academic ML research and robust production systems. You possess a solid mathematical foundation and a deep understanding of modern ML architectures, combined with the technical skills to write clean and highly optimized PyTorch code. You take pride in creating core tooling that empowers research teams to move fast without breaking everything.

Key Responsibilities

  • Core Tooling & Infrastructure: Build and maintain the engineering infrastructure that allows the research team to iterate rapidly and safely. Owns "Build vs. Buy" and open-source adaptation strategies that shape the 1–2 year technical roadmap.
  • Bridge Research & Engineering: Refactor, optimize, and add engineering rigor to messy, script-like experimental research code without stifling discovery. Establish team-wide guardrails, templates, and mentor researchers on engineering best practices.
  • Model Implementation: Implement, train, and evaluate modern deep learning architectures from scratch using PyTorch. Successfully translate dense, math-heavy research papers into functional software.
  • Testing & Troubleshooting: Rigorously test and troubleshoot complex ML systems to ensure both software correctness and optimal computational efficiency. Formulate hypotheses to independently diagnose convergence issues and data bottlenecks.
  • Cross-Functional Collaboration: Partner closely with dedicated MLOps and Data Engineering teams to seamlessly transition research models into existing production pipelines.

Qualifications

Basic Qualifications

  • Mathematics: Solid foundational grasp of linear algebra, calculus, and probability.
  • Deep Learning: Strong understanding of modern machine learning/deep learning architectures and training dynamics.
  • PyTorch Proficiency: Highly proficient in PyTorch, including model building and basic optimization.
  • Software Engineering: Strong general programming skills, with practical experience handling concurrency, threading, memory management, and debugging.
  • Ambiguity Tolerance: High tolerance for ambiguity and a willingness to work hands-on with unstructured, messy research scripts.

Preferred Qualifications

  • Advanced PyTorch & Infrastructure: Extensive knowledge of PyTorch internals, distributed training paradigms, custom operators (e.g., CUDA/Triton kernels), and advanced performance profiling.
  • Mangement & Strategy: Experience managing large-scale data pipelines and partnering with MLOps.
  • Tooling: Familiarity with ML experiment tracking tools (e.g., Weights & Biases), workflow orchestration (e.g., Airflow), Kubernetes, and containerization (Docker) on cloud platforms (e.g., GCP).
  • Domain Interest: Domain knowledge or a strong interest in computational biology (prior biology expertise is not required).

What You'll Gain & Impact

  • Direct Patient Impact: Your engineering work will directly impact the creation of new genetic medicines for patients with unmet needs.
  • Foundation Models: The opportunity to build Biological Foundation Models that map genetic inputs to downstream molecular mechanisms and patient outcomes.
  • Scientific Immersion: Partner with computational biologists and wet-lab scientists, gaining the deep scientific context needed to maximize your engineering impact.
  • Publications: Opportunities to publish and present work focusing on AI for genome biology and medicine.

What We Offer

  • Compensation: Highly competitive compensation, including meaningful stock ownership.
  • Comprehensive Benefits: Health, vision, and dental coverage for employees and families, alongside an employee and family assistance program.
  • Flexibility & Time Off: Flexible work environment (including flexible hours), extended long weekends, holiday shutdown, and unlimited personal days.
  • Family Support: Maternity and parental leave top-up coverage, as well as new parent paid time off.
  • Growth: Learning and development budget alongside regular educational lunch-and-learns.

Profluent
Permanent
June 22, 2026

Biotech Project Manager, Early Discovery

$115,000 - $150,000
Emeryville, CA
Hybrid

Profluent is an AI-first protein design company developing deep generative models to invent novel, functional proteins that revolutionize biomedicine. Founded in 2022 and headquartered in Emeryville, CA, Profluent fuses generative AI with high-throughput experimental biology. Backed by top-tier investors (including Altimeter Capital, Bezos Expeditions, and Spark Capital), the company has raised over $150M to date.

Role Overview

  • Position: Project Manager
  • Location: Emeryville, CA
  • Base Compensation Range: $115,000 - $150,000 / year
  • Sponsorship: None (Requires ongoing U.S. work authorization without future sponsorship)

The Project Manager acts as the operational backbone of Profluent's internal and external programs. Partnering directly with Alliance Management and scientific teams, this role translates complex scientific contracts, Statements of Work (SOWs), and partner milestones into highly organized, visual, and trackable project plans. You will map out and manage cross-functional critical paths across machine learning model training loops, bioinformatics pipelines, and wet-lab validation sprints.

Responsibilities

Timeline & Milestone Mapping

  • Translate partner milestones, research plans, and scientific contracts into day-to-day internal execution plans.
  • Create, monitor, and dynamically update detailed Gantt charts across multiple concurrent programs to map out critical paths, resource dependencies, and delivery dates.
  • Align internal Agile sprints across Machine Learning, Bioinformatics, and Wet Lab Biology teams with external alliance timelines.

Risk Management & Tracking

  • Partner closely with the Alliance Manager to monitor project health, proactively identifying timeline variances, resource bottlenecks, or potential delays.
  • Track project workstreams to ensure compliance with partner milestone triggers, routine quarterly reporting rhythms, and material transfer protocols.
  • Provide data-driven updates, burn-down charts, and timeline visualizations using project mapping tools and ML/Bioinformatics dashboards for internal leadership and external Joint Steering Committees.

Process Optimization

  • Develop and implement lightweight, user-centered project management workflows that improve team velocity and coordination while minimizing administrative overhead.

Qualifications

Minimum Requirements

  • Experience: 3–5 years of dedicated project management experience within the biotechnology, pharmaceutical, or life sciences industry.
  • Education: BA/BS in Molecular Biology, Computational Biology, or a closely related scientific field. Must understand the operational timelines associated with wet-lab gene-editing systems and AI model training loops.
  • Technical Tooling: Proven track record of managing complex, multi-variable project timelines and cross-functional dependencies using Jira and Smartsheet.
  • Contract Competency: Experience reviewing scientific contracts, research plans, and SOWs to extract operational deliverables.
  • Core Skills: Exceptional cross-functional communication, stakeholder management, and meticulous organizational skills. Ability to lead and coordinate complex technical domains through influence without direct authority.

Preferred Attributes

  • Certifications: Active PMP (Project Management Professional), PRINCE2, PMI-ACP, or a Senior Scrum credential.
  • Advanced Jira Skills: Experience configuring custom Jira workflows, managing complex backlogs, and utilizing roadmap plugins (e.g., Advanced Roadmaps, Structure).
  • Environment: Experience thriving in early-stage, fast-paced, and ambiguous startup environments.

What Profluent Offers

  • Competitive base salary with meaningful equity participation.
  • Comprehensive medical, dental, and vision insurance.
  • 401(k) retirement plan with a strong employer match.
  • Generous Paid Time Off (PTO) policy promoting work-life balance.
  • Dedicated professional development opportunities at the cutting edge of AI and biology.

Equal Opportunity & Compliance

Profluent Bio, Inc. is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status, or any other characteristic protected by law. Legal authorization to work in the United States and compliance with federal employment eligibility verification (Form I-9) is required upon hire.

BillionToOne
Permanent
June 22, 2026

Data Scientist, Prenatal

TBD
Menlo Park, CA
Onsite

BillionToOne is a category-defining, publicly traded molecular diagnostics company on Nasdaq that has grown from $0 to a $400M+ annualized revenue run-rate in just 6 years. Utilizing their proprietary QCT molecular counting technology, they build life-changing prenatal and cancer diagnostic products (such as Unity Complete™, Unity Confirm™, and Northstar®) that are 10x better than anything existing today.

Role Overview

  • Position: Data Scientist (Prenatal Data Team)
  • Location: Menlo Park, CA / Union City, CA (Headquarters)
  • Type: Full-Time, Full-Stack Analytics

Data scientists at BillionToOne are "full-stack" contributors who span the entire analytics value chain. In this role, you will wear a data engineering hat to land data into a central warehouse, an analytics engineering hat to model and test it, and a data science hat to build dashboards, deploy AI-powered analysis workflows, and surface insights that drive decisions across commercial, laboratory, clinical, and executive teams.

Responsibilities

Full-Stack Analytics & Engineering

  • Contribute across the full Prenatal analytics stack by ingesting data from disparate sources into the central data warehouse.
  • Build clean, well-tested data models and maintain the central data warehouse architecture while partnering with upstream operational system owners (e.g., Clarity, bioinformatics pipelines).
  • Develop and maintain Tableau dashboards and self-serve tooling to turn raw metrics into actionable insights for clinical, commercial, and operational teams.

Cross-Functional Stakeholder Partnership

  • Partner directly with cross-functional teams to tackle high-stakes business questions (e.g., optimizing lab turnaround times, identifying at-risk commercial accounts, tracking product launches, and supporting clinical affairs).
  • Translate data findings into clear, strategic answers to inform executive growth decisions.

AI Integration & Automation

  • Leverage advanced AI tools daily to accelerate your personal analysis and engineering velocity.
  • Build and scale HIPAA-compliant, AI-powered analysis workflows for the team.
  • Act as an internal advocate, helping non-technical colleagues across the organization adopt AI tools to maximize productivity.

Qualifications

Minimum Requirements

  • Education & Experience:
    • Master's or PhD with 2 years of professional experience, OR
    • Bachelor's degree with 4 years of professional experience in data science, analytics engineering, or a related data role.
  • Technical Stack: Strong proficiency in SQL and Python (or R) for complex data manipulation and statistical analysis.
  • Data Maturity: Comfort working with messy, unstructured, and disparate data sources, alongside the judgment to know when to clean data locally versus pushing fixes upstream.
  • Domain Context: Direct experience working with clinical, healthcare, or other highly regulated data.
  • AI Tooling: Hands-on experience using generative AI tools to enhance engineering workflows, combined with a strong interest in enabling others to do the same.
  • Professional Attributes: Exceptional communication skills and a deep sense of ownership over data quality and stakeholder outcomes.

Nice-To-Haves

  • Technical Tools: Familiarity with dbt, Airflow, Tableau, Stitch, Hightouch, Cursor, Claude, ChatGPT, AWS (S3, Batch, RDS, MWAA), or Clarity.
  • Industry Domain: A background in biosciences or familiarity with bioinformatics, molecular diagnostics, lab sales cycles, prior authorization, and healthcare reimbursement.

Compensation, Benefits & Perks

BillionToOne offers a flexible total rewards structure combining a competitive base salary (tailored to experience and a candidate-selected salary/equity split), a corporate bonus program, and a comprehensive equity options package.

  • Health & Wellness: Multiple medical options with 100% employee premium coverage on select plans; dependents covered up to 80%. Supplemental fertility benefits are also included.
  • Family Support: Exceptionally generous Family Bonding Leave (16 weeks, fully paid at 100%).
  • Retirement: 401(k) program with a 4% company match.
  • Time Off: Paid time off allotments that scale upward with your tenure.
  • On-Campus Amenities: Free daily catered lunches from top local eateries, a state-of-the-art corporate gym, an on-site restaurant, and free EV charging stations (compatible with all EVs, including Tesla).

Corporate Culture & Privacy

BillionToOne maintains an open, transparent culture supported by weekly company-wide Town Hall meetings. They are Great Place to Work certified and were named by Forbes as one of America's Best Startup Employers.

To review how candidate information is handled during the recruitment process, please consult the BillionToOne Privacy Policy. As an equal opportunity employer, BillionToOne prohibits discrimination on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Altos Labs
Permanent
June 22, 2026

Scientist / Senior Scientist, Metabolomics Group Lead

$156,800 - $221,000
Redwood City, CA
Onsite

Altos Labs is a mission-driven biotechnology company focused on restoring cell health and resilience through cell rejuvenation to reverse disease, injury, and disabilities. Named one of the Top 3大 Biotech Companies and ranked on the Forbes Best Startups in America list, Altos Labs brings together exceptional global scientists and industry leaders within an inclusive, collaborative culture centered on scientific excellence and belonging.

Role Overview

  • Position: Scientist / Senior Scientist, Metabolomics Group Lead
  • Location: Redwood City, CA
  • Schedule: Onsite
  • Base Compensation Ranges:
    • Scientist II: $156,800 - $201,000 / year
    • Senior Scientist: $172,400 - $221,000 / year

The Mass Spectrometry Hub sits within the Institute of Technology, utilizing an array of cutting-edge instrumentation. The Metabolomics Group Lead is responsible for the end-to-end management of metabolomics and lipidomics projects—spanning experimental design, sample preparation, measurement, data processing, and delivery. This role collaborates closely with scientific and bioinformatics teams to guarantee robust data generation and maintain operational excellence across liquid chromatography-mass spectrometry (LC-MS) platforms.

Responsibilities

Project Management & Collaboration

  • Collaborate with cross-functional scientists to define project objectives, assess technical feasibility, and establish clear deliverables and timelines.
  • Maintain accurate, up-to-date project tracking and documentation using Benchling and shared project management tools.
  • Communicate project status, timelines, and potential risks effectively to internal stakeholders and leadership.

Lab Operations & Sample Processing

  • Execute and supervise sample preparation workflows for steady-state metabolomics and lipidomics.
  • Optimize and adapt extraction protocols to support the analysis of diverse and challenging biological samples (cells, tissues, and biofluids).
  • Operate, maintain, and troubleshoot LC-MS instrumentation—including the Thermo Exploris 240, SCIEX 7500, and Vanquish HPLC—to ensure optimal performance and minimize instrument downtime.

Data Analysis & Bioinformatics

  • Process and analyze raw datasets using specialized software such as Skyline and Compound Discoverer.
  • Coordinate with bioinformatics teams to ensure accurate data processing, rigorous quality control (QC), and efficient project execution.

Qualifications

Minimum Requirements

  • Education: PhD (or equivalent experience) in metabolomics, lipidomics, analytical chemistry, biochemistry, or a related discipline.
  • Mass Spectrometry Expertise: More than 6 years of hands-on experience with both High-Resolution Accurate Mass (HRAM) and Low-Resolution Mass Spectrometry (LRMS) platforms. Preferred experience specifically includes Orbitrap Exploris and SCIEX triple quadrupole mass spectrometry platforms.
  • Experimental Design: Strong experimental design and problem-solving skills, with direct experience performing sample preparation on cells, tissues, and biofluids.
  • Leadership & Mentorship: Demonstrated experience mentoring team members and managing collaborative projects with scientists from diverse training backgrounds.

Preferred Attributes (Ideal candidates satisfy 2 or more)

  • Experience developing completely new methods for the analysis of metabolites or lipids of interest.
  • Prior experience in Metabolite Identification (MetID) and trapping within the context of drug metabolism.
  • Experience executing large-scale discovery studies exceeding 1,000 samples.
  • Experience designing and interpreting complex isotope tracing experiments (e.g., metabolic flux analysis).
  • Experience integrating metabolomics/lipidomics datasets with other multi-omics modalities, such as proteomics and transcriptomics.

Company Culture & Protections

Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.

Equal Opportunity Employer

Altos Labs provides equal employment opportunities to all employees and applicants without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by law.

Candidate Security & Scam Notice

Altos Labs will never ask you to download a third-party messaging app for an interview, nor will they require an outlay of your own money to begin employment. If you experience an interaction matching this description from individuals claiming to represent the company, it is a fraudulent job scam.

Element Biosciences
Permanent
June 12, 2026

Technical Applications Scientist

$90,000 - $110,000
San Diego, CA
Onsite

At Element Biosciences, we are passionate about our mission to empower the scientific community with more freedom and flexibility to accelerate our collective impact on humanity. We have built a highly efficient product-driven organization where employees can learn, grow, and thrive in a challenging but encouraging environment. We are committed to scientific integrity, collegiality, honesty, objectivity, and openness.  

We are seeking an experienced Technical Applications Scientist who will play a pivotal role in addressing applications and informatics inquiries and concerns for our customers. This position requires exceptional technical proficiency, customer management skills, and an ability to work cross functionally with Commercial and R&D partners to deliver a strong end user experience.  

Role Overview

  • Location: San Diego, CA (Onsite at Headquarters)
  • Job Type: Full-time / Exempt
  • Reporting To: Senior Manager of Technical Support
  • Base Compensation Pay Range: $90,000 - $110,000

Essential Functions and Responsibilities

  • Frontline Customer Support: Provide frontline customer support for applications and informatics related customer inquiries and issues.
  • Triage & Escalation: Triage general customer complaints and delineate applications vs. software vs. hardware issues that may require the dispatching of Element Field Service Engineers or Field Application Scientists. Support the management of applications and informatics customer escalations requiring internal R&D and Operations support.
  • Troubleshooting & Log Analysis: Review instrument run logs and query databases to identify and troubleshoot issues over the phone or email. Identify root causes to applications and informatics issues and propose recommendations to influence and drive customer success.
  • Strategy & Documentation: Develop creative and effective support strategies, guidance to service manuals, and creation of procedures for new products and product updates. Develop and validate applications and informatics troubleshooting documentation.
  • Internal Collaboration: Partner with Software Development and Applications teams to provide appropriate technical solutions to customer analysis workflows. Provide customer feedback to internal teams to drive design change recommendations with a strong end-user focus.
  • Team Training: Provide technical guidance to tech support and field applications peers. Provide the broader customer support team with troubleshooting debriefs and regular updates/training on applications and informatics changes.
  • CRM Tracking: Utilize service CRM software to dispatch and accurately document work in a timely manner, displaying professionalism, understanding, tact, and technical knowledge in all customer interactions.

Education and Experience

  • Education: Bachelor's Degree in molecular biology, genetics, bioinformatics, or a related field. A Master's Degree is a plus.
  • Industry Experience: Minimum 1 year of experience with customer support and/or working in the biotech industry.
  • Technical Experience: Experience parsing large instrument logs to identify common patterns to drive action.
  • Preferred Experience (Plus): * Familiarity with Multi-omics workflows.
    • Experience working with instrumentation featuring optics, microfluidics, and electromechanical systems.
  • Communication Skills: Excellent verbal and written communication skills, with proven technical writing abilities.

Physical Requirements, Travel, & Schedule

  • Physical Limits: Ability to lift up to 20 pounds.
  • Schedule: Must be flexible in working hours as this position may require customer support during non-regular business hours.
  • Travel: Domestic and International travel up to 10%.

Compensation & Total Rewards

The base compensation range for this role is $90,000 - $110,000. Base compensation will depend on multiple factors, including geographic location, qualifications, and experience.

In addition to base compensation, you will be eligible for:

  • Stock options
  • Discretionary annual bonus
  • No-cost health insurance plans
  • 401(k) with company match
  • Flexible paid time off

Equal Opportunity Employment

We foster an environment such that all people are afforded the freedom to pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation, gender identity or expression, age, disability, veteran status or any other characteristics protected by law.  

Biohub
Permanent
June 8, 2026

Senior / Staff Data Engineer

$241,000 – $338,000
New York, NY (Hybrid); Redwood City, CA (Hybrid)
Hybrid

Our Mission

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.

The Team

Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.

The Opportunity

The role is part of the Data Engineering team, which focuses on owning the strategy, sourcing and implementation for data supporting AI research and development. Our goal is to maximize the speed, agility, and capability of biological AI research by connecting public data resources and Biohub's experimental platforms to AI systems. The data that trains biological frontier models comes in dozens of modalities (sequences, images, spatial coordinates, time series, molecular structures, metadata, publication artifacts) each with its own noise characteristics, biases, and information content. The question of how to represent this data for learning is one of the most important open problems in biological AI.

As a data engineer at Biohub, you'll be designing systems that ingest data from public repositories, transform heterogeneous biological formats into AI-ready datasets, combine that with proprietary datasets, and deliver training datasets to researchers pushing the boundaries of what's possible in biological AI. The infrastructure you build will directly shape what our models can learn.

We're a small team with significant resources and long time horizons. We use AI tools aggressively in our own work—Claude Code, agents for workflow automation, LLMs for metadata extraction. We care about code quality, operational reliability, and building systems that scale. And we care about the biology: we want engineers who can recognize when a pipeline output is technically correct but scientifically wrong.

If you want to work at the intersection of large-scale infrastructure and frontier science, with real autonomy and the chance to build something genuinely new, we'd like to talk.

What You'll Do

  • Design and build data pipelines that process genomic and imaging data at petabyte scale
  • Solve performance and bandwidth challenges with creative engineering
  • Build agent-based systems for automated dataset curation, quality control, and workflow generation
  • Create tooling for data cataloging and registration that makes datasets discoverable and accessible
  • Collaborate with AI Research teams to translate model requirements into data specifications, and with our scientists to integrate public and internal data into large-scale ai-ready datasets
  • Improve pipeline reliability and observability, working toward 99%+ success rates without manual intervention

What You'll Bring

  • 8+ years experience building reliable, operable data systems at scale (100s terabytes to petabytes)
  • Strong software engineering fundamentals
  • Experience deploying distributed computing frameworks like Databricks, Spark, or Ray for large-scale data processing
  • Experience with cloud infrastructure (AWS preferred) and HPC environments
  • Comfort with ambiguity; ability to make progress when requirements are evolving
  • Interest in AI-native development practices and tooling
  • Nice to have: Background in computational biology, bioinformatics, or life sciences and experience with genomics datasets and formats (FASTQ, BAM, VCF) or imaging formats (OME-Zarr, HDF5)

Compensation

The future anticipated Redwood City, CA, and New York City, NY base pay range for a role in this field is $241,000–$338,000 annually. Compensation ranges will vary based on job-related skills, level of experience, and knowledge. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

Better Together

As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

Benefits for the Whole You

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

  • Provides a generous employer match on employee 401(k) contributions to support planning for the future.
  • Paid time off to volunteer at an organization of your choice.
  • Funding for select family-forming benefits.
  • Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.  

Precede Biosciences
Permanent
June 8, 2026

Associate Director/Director, Computational Test Development

N/A
Boston, MA
Onsite

The Opportunity

We are seeking an Associate Director/Director-level computational scientist to drive the analytical and regulatory dimensions of diagnostic test development at Precede Biosciences. Reporting to the Senior Director of Computational Test Development, this role sits at the center of our effort to bring a novel epigenomics-based liquid biopsy platform from late-stage development through FDA regulatory submission.

You will lead the analytical strategy and bioinformatics infrastructure verification that underlies our validation programs. You will drive the interpretation of complex data, guide pipeline execution, and author critical regulatory documentation in close partnership with laboratory, clinical, and regulatory teams.

About Us

We are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. More information on our company and platform can be found on our company website and in our seminal publication in Nature Medicine.  

We care deeply about creating a place where folks can do their best work from the start and have intentionally created an environment that is defined by purpose, teamwork, and excellence. This means nurturing team spirit, facing challenges together, and collaboratively solving complex problems, while also ensuring a strong focus on individual initiative, accountability, and delivery.  

What You'll Do

Analytical Validation & Regulatory Execution

  • Design and develop computational approaches for characterizing the performance of existing and new epigenomic tests.
  • Define and implement metrics and analyses to assess NGS and epigenomic data quality to enable coordinated optimization of assay and diagnostic performance.
  • Lead the computational execution of verification and validation protocols, statistical analysis plans (SAPs), and performance summary reports to meet FDA evidentiary standards.
  • Translate complex computational results into clear, well-organized regulatory documentation for FDA submissions.
  • Stay current on FDA guidance for IVDs, companion diagnostics, and evolving LDT oversight to actively inform study design decisions.

Statistical & Bioinformatics Analysis

  • Develop and apply statistical methods for diagnostic characterization, including LOD/LOQ, reproducibility, thresholding, guardbanding, and clinical utility endpoints.
  • Support and optimize robust, reproducible analysis pipelines—ensuring code traceability and standardization from raw NGS data through regulatory-grade outputs.
  • Identify and systematically address sources of variability, bias, and technical confounding across the computational workflow.

Cross-Functional Collaboration

  • Partner closely with laboratory development, clinical operations, and regulatory affairs to ensure absolute scientific and regulatory alignment across programs.
  • Contribute to clinical study design—including sample size calculations, endpoint selection, and pre-specified SAPs using data-driven insights from analytical validation pilots.

What You'll Bring

  • PhD in computational biology, bioinformatics, biostatistics, or a closely related quantitative field. Direct experience with advanced NGS modalities (e.g., cell-free DNA, ChIP-Seq, or epigenomic signal processing) is highly preferred.
  • 4–9 years of industry experience in regulated diagnostics, liquid biopsy, or IVD development, ideally within a fast-paced, cross-functional R&D environment.
  • Proven track record working under a formal Quality Management System (ISO 13485, 21 CFR Part 820).
  • Hands-on experience contributing to regulatory submissions (such as Pre-Subs, De Novo, or 510(k) tracks). Please describe your specific role and submission type in your cover letter or CV.
  • Solid grasp of analytical validation frameworks, including CLSI EP guidelines, FDA IVD/CDx guidance, and CAP/CLIA requirements.
  • Fluency in R and/or Python for robust statistical modeling, data analysis, and reproducible reporting.
  • Strong communication skills with a demonstrated ability to present and defend analytical validation strategies to internal leadership, scientific advisors, and regulatory stakeholders.
  • Startup mindset: You thrive when taking autonomous ownership of projects, remain adaptive under evolving information, and execute effectively in an entrepreneurial environment.

Profluent
Permanent
June 8, 2026

Machine Learning Scientist, BioML

$200,000 — $330,000
Emeryville, California
Hybrid

Our Mission

Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

We're looking for a motivated and creative Machine Learning (ML) Scientist to drive research into models at the intersection of complex protein biology and AI. This position offers an opportunity to work at the forefront of generative modeling research across language processing, representation learning, and protein engineering. You should be a self-directed researcher who has the ability to rapidly prototype and evaluate new models and algorithms in the biomolecular domain.

As an early employee, you will proactively shape the direction of our machine learning efforts and collaborate across diverse teams of computational and experimental scientists.

Responsibilities

  • Design and develop state-of-the-art predictive and generative models incorporating domain-specific evolutionary and experimental data
  • Leverage massive-scale protein and nucleic acid data to train specialized models for protein understanding and design
  • Curate relevant datasets and design tasks for rigorous evaluation of generative models
  • Collaborate across the machine learning and protein design teams to adapt and apply techniques for experimental validation
  • Implement, analyze, and interpret multiple computational approaches and present results to colleagues in regular update meetings  
  • Work within a collaborative, fast-paced, interdisciplinary team across biology and machine learning to help shape the scientific and strategic vision of the company  

Qualifications

  • PhD (or equivalent industry experience) in Computer Science, Machine Learning, Natural Language Processing, Applied Math, Computational Biology, Statistics, or a related field
  • Experience with conceiving of, implementing, and evaluating novel machine learning techniques at the intersection with biology
  • Publications at major machine learning conferences (NeurIPS, ICML, ICLR) or scientific journals (Nature, Science, Nature Biotech, Nature Methods, PNAS)
  • Experience with modern deep learning frameworks such as PyTorch or Jax

Preferences

  • Familiarity with foundational biology of proteins and nucleic acids  
  • Experience developing machine learning models for proteins (language models, structure prediction, design)  
  • Experience with cloud compute platforms (GCP, AWS, Azure, OCI)  
  • Previous experience in data extraction and curation from bioinformatics data sources
  • Familiarity with wet lab experimental assays and associated limitations
  • 3 to 5 years of industry experience

What We Offer

  • High-growth opportunity with meaningful impact on the future of protein design
  • Competitive compensation package with equity participation
  • 401(k) with a strong employer match
  • Comprehensive benefits including health/dental/vision insurance
  • Generous PTO policy and commitment to work-life balance
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology

Hiring Salary Range

$200,000 — $330,000 USD

Employment Eligibility & Equal Opportunity

Profluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.  

Legal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire.  

Profluent
Permanent
June 5, 2026

Scientist II - Sr. Scientist, CRISPR Specificity & Genomic Safety

$147,000 — $177,000
Emeryville, California
Onsite

Our Mission

Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

Profluent is seeking a creative and enthusiastic Scientist II - Sr. Scientist to build and apply experimental workflows that characterize the specificity, safety, and developability of our personalized CRISPR base editing platform. This role will initially focus on establishing and scaling base-editor specificity workflows, including biochemical and cell-based approaches such as CHANGE-seq-BE and related methods for identifying DNA and RNA off-target activity. In the longer term, the candidate will spearhead off-target assessments for novel gene editing platforms such as engineered recombinases.

The candidate will work closely with protein engineering, cell biology, bioinformatics, automation, and program teams to generate decision-quality datasets that guide editor design, candidate selection, and therapeutic program development. This person will be responsible for benchmarking assays, interpreting NGS-based specificity data, identifying limitations and opportunities across methods, and building robust workflows that can be deployed across editing modalities and disease-relevant contexts.

This is an excellent opportunity to shape how AI-designed genome editing systems are evaluated and advanced, and to work cross-functionally with a diverse team of experts across machine learning, protein engineering, cell biology, genomics, and gene editing.

Responsibilities

  • Build and lead Profluent’s strategy for base editor specificity assessment, with an emphasis on base-editor-relevant off-target discovery and validation workflows such as CHANGE-Seq-BE and related biochemical, cell-based, and targeted sequencing approaches
  • Develop, optimize, benchmark, and apply orthogonal methods to evaluate editing specificity, including workflows for base editors, nucleases, and broader genomic integrity assessment across relevant experimental systems
  • Design and execute studies to identify, prioritize, and validate potential off-target editing events, integrating assay development, NGS library preparation, sequencing QC, and data interpretation in partnership with computational biology and program teams
  • Generate high-quality, decision-enabling datasets that inform editor engineering, guide/editor selection, delivery conditions, candidate nomination, and program development strategy
  • Collaborate cross-functionally with protein engineering, cell biology, gene editing, bioinformatics, automation, and program teams to integrate specificity workflows into Profluent’s broader R&D infrastructure
  • Establish robust experimental processes, documentation, and analysis frameworks to support reproducibility, scalability, assay qualification, and potential regulatory-facing genomic safety packages
  • Present results and clearly communicate experimental strategy, timelines, risks, milestones, and program implications to diverse scientific and company stakeholders
  • Provide mentorship and guidance to junior team members and peers, helping align goals, troubleshoot experiments, and maintain high standards for execution and interpretation
  • Stay current with emerging technologies in CRISPR specificity, base editing, off-target discovery, targeted validation, genomic integrity assessment, and therapeutic genome editing

Qualifications

  • PhD (or equivalent) in molecular biology, genomics, genome editing, biochemistry, bioengineering, genetics, chemical biology, or a related field with 2-4 years of relevant industry experience in genome editing specificity and genomic safety assessment
  • Deep expertise and hands-on experience with CRISPR-based genome editing systems, particularly base editors, and a strong understanding of modality-specific specificity risks such as DNA off-target editing, RNA off-target editing, bystander editing, indels, and unintended editing outcomes
  • Hands-on experience developing, optimizing, or applying NGS-based workflows for genome editing analysis, such as CHANGE-seq, CHANGE-seq-BE, GUIDE-seq, SITE-seq, CIRCLE-seq, Digenome-seq, DISCOVER-seq, INDUCE-seq, targeted amplicon sequencing, rhAmpSeq/AmpSeq-like workflows, hybrid capture, RNA-seq, WGS, or related approaches
  • Strong experimental background in molecular biology, mammalian cell culture, genome editing reagent delivery, NGS library preparation, assay troubleshooting, and quantitative analysis of editing outcomes
  • Experience interpreting complex sequencing datasets and collaborating with bioinformatics or computational biology teams to analyze off-target discovery, targeted validation, variant calling, RNA editing, indel profiles, or genomic integrity data
  • Ability to design rigorous experiments with appropriate controls, replicates, sensitivity considerations, and clear decision criteria
  • Experience with high-throughput or semi-automated workflows, process development, assay qualification, data tracking, and reproducible execution in a fast-paced research environment
  • High level of attention to detail and commitment to generating high-quality, decision-enabling data
  • Experience with cross-functional collaboration in a biotechnology setting, particularly with protein engineering, cell biology, computational biology, translational, or program teams
  • Excellent communication skills and ability to present complex scientific concepts, datasets, limitations, and recommendations to colleagues and stakeholders
  • Strong track record of managing complex projects, mentoring junior scientists, and driving workstreams from exploratory development through implementation

Preferences

  • Experience with therapeutic genome editing programs and genomic safety packages for candidate nomination, IND-enabling studies, or regulatory-facing documentation
  • Experience working with disease-relevant primary cells, ex vivo edited cells, iPSC-derived systems, or other therapeutically relevant model systems
  • Familiarity with ML-guided enzyme engineering campaigns and how specificity datasets can inform editor design, model evaluation, and candidate prioritization
  • Expertise in protein purification of genome editors for use in biochemical off-target assays

What We Offer

  • High-growth opportunity with meaningful impact on the future of protein design
  • Competitive compensation package with equity participation
  • 401(k) with a strong employer match
  • Comprehensive benefits including health/dental/vision insurance
  • Generous PTO policy and commitment to work-life balance
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology

Hiring Salary Range

$147,000 — $177,000 USD

Requirements & Equal Opportunity

Work Authorization Requirement

Applicants must have ongoing work authorization in the United States that does not require employer sponsorship. Sponsorship will not be provided now or at any time in the future for this position.

Employment Eligibility Verification

Legal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire.

Equal Opportunity Employer

Profluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.  

Profluent
Permanent
June 5, 2026

Machine Learning Scientist, Reinforcement Learning

$200,000 — $330,000
Emeryville, California, United States
Hybrid

Our Mission

Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

We're looking for a motivated and creative Machine Learning (ML) Scientist to drive research into reinforcement learning for biomolecular design. This position offers an opportunity to work at the forefront of generative modeling research across language processing, representation learning, and protein engineering. You should be a self-directed researcher who has the ability to rapidly prototype and evaluate new models and algorithms in the biomolecular domain.

As an early employee, you will proactively shape the direction of our machine learning efforts and collaborate across diverse teams of computational and experimental scientists.

Responsibilities

  • Design and develop state-of-the-art online and offline reinforcement learning algorithms for protein design
  • Collaborate across the machine learning and protein design teams to adapt and improve reinforcement learning techniques from other domains to protein design
  • Architect, implement, and optimize core infrastructure to support the post-training of protein language models
  • Curate relevant datasets and design tasks for rigorous evaluation of generative models
  • Implement, analyze, and interpret multiple computational approaches and present results to colleagues in regular update meetings  
  • Work within a collaborative, fast-paced, interdisciplinary team across biology and machine learning to help shape the scientific and strategic vision of the company  

Qualifications

  • PhD (or equivalent industry experience) in Computer Science, Machine Learning, Natural Language Processing, Applied Math, Computational Biology, Statistics, or a related field
  • Experience with conceiving of, implementing, and evaluating novel machine learning and reinforcement learning techniques
  • Publications at major machine learning conferences (NeurIPS, ICML, ICLR) or scientific journals (Nature, Science, Nature Biotech, Nature Methods, PNAS)
  • Experience with modern deep learning frameworks such as PyTorch or Jax

Preferences (but not required)

  • Familiarity with foundational biology of proteins and nucleic acids  
  • Experience developing machine learning models for proteins (language models, structure prediction, design)  
  • Experience with cloud compute platforms (GCP, AWS, Azure, OCI)  
  • Previous experience in data extraction and curation from bioinformatics data sources
  • Familiarity with wet lab experimental assays and associated limitations

What We Offer

  • High-growth opportunity with meaningful impact on the future of protein design
  • Competitive compensation package with equity participation
  • 401(k) with a strong employer match
  • Comprehensive benefits including health/dental/vision insurance
  • Generous PTO policy and commitment to work-life balance
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology

Hiring Salary Range

$200,000 — $330,000 USD

Employment Eligibility & Equal Opportunity

Profluent Bio, Inc is an equal opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.  

Legal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire.

BillionToOne
Permanent
May 29, 2026

Research Associate

$75,029 - $85,748
Menlo Park, CA
Onsite

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

Research Associate

The Research Associate position at BillionToOne is exceptionally rare at the undergraduate or early-career level. At BillionToOne, you will do much more than simply run routine protocols. Your work will shape the development of high-impact molecular diagnostic products that are actively changing patient outcomes in both oncology and prenatal medicine. This is your chance to contribute to building novel molecular tests that help patients from day one.

You will work alongside and be mentored by scientists with interdisciplinary expertise across molecular biology, genomics, bioinformatics, and quantitative modeling. You will have the chance to use cutting-edge molecular techniques, next-generation sequencing, and robotic tools to move assays from research prototypes to analyzing thousands of real patient samples in our clinical lab as a commercially available product. Whether your ambition is to grow here at BillionToOne or ultimately pursue graduate studies, this position would be a solid foundation for your scientific career.

Role Overview

  • Location: Menlo Park, CA (On-site)
  • Base Pay Range: $75,029 - $85,748 per year
  • Total Compensation Package: Up to $104,322 per year (including a generous equity options offering and corporate bonus program)

Who We’re Looking For:

  • Strong statistical and quantitative skills: You think rigorously about data. You understand the difference between signal and noise, appreciate the importance of statistical power, and bring quantitative reasoning to every problem.
  • Meticulous attention to experimental detail: You understand that the quality of an experiment determines what we can learn from it. You keep rigorous records, design careful controls, and take pride in work that others can rely on and build upon.
  • Ambition to make a difference now: You aren’t here to punch the clock. You want to understand why things work, push the boundaries of what’s known, and do what it takes to see your contributions show up in products that help real patients.

Responsibilities:

  • Design, execute, and troubleshoot experiments and assays under the guidance of Senior Scientists
  • Learn analytical and computational methodologies to analyze results under the guidance of Senior Scientists
  • Present scientific findings both verbally at group meetings and via internal written reports
  • Document experimental details and results
  • Collaborate with other teams to implement lab and bioinformatic workflows
  • Contribute positively to organizing and maintaining the R&D lab

Qualifications:

  • BS or MS in Bioengineering, Molecular and Cell Biology, Microbiology, Biophysics, Biochemistry, or related field
  • 1–2 years of research experience (either during BS/MS or afterwards)
  • Previous experience with standard molecular biology techniques (in particular, extensive experience with PCR, electrophoresis, DNA purifications)
  • An ability to quickly learn mathematical, analytical, and experimental concepts
  • High mathematical and statistical aptitude (e.g., you find the GRE math section to be extremely easy)
  • Great attention to detail

Nice-To-Haves:

  • Start-up experience
  • Knowledge of medical genetics
  • Experience in a cell-free DNA setting
  • Experience with next-generation sequencing library preparation
  • Experience with computational analysis in R, Python, or other programming language

Benefits And Perks:

  • Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
  • Open, transparent culture that includes weekly Town Hall meetings
  • The ability to indirectly or directly change the lives of hundreds of thousands patients
  • Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
  • Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
  • Supplemental fertility benefits coverage
  • Retirement savings program including a 4% Company match
  • Increase paid time off with increased tenure
  • Latest and greatest hardware (laptop, lab equipment, facilities)
  • Daily on-site lunches provided from top eateries
  • A variety of perks on campus (state of the art gym, restaurant)
  • Free on-site EV charging (compatible with all EVs, including Tesla)

Our Impact, Growth & Future

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA, a breakthrough that has already transformed the lives of over half a million patients worldwide.

  • Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
  • Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding, including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest. Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com

Equal Opportunity Employment

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

For more information about how we protect your information, we encourage you to review our Privacy Policy.

GATC Health
Permanent
May 22, 2026

Bioinformatics Analyst - UT

N/A
Salt Lake City, UT
Onsite

Company Overview:

GATC Health is an innovative TechBio company at the forefront of revolutionizing pharmaceutical discovery and accelerating their development through the integration of artificial intelligence (AI), science and finance. Our company is dedicated to advancing therapeutic discoveries and improving human health by leveraging the power of technology and interdisciplinary collaboration.

Position Overview:

We are seeking a talented Bioinformatics Analyst to join our dynamic, multi-disciplinary team that is responsible for implementing and aiding in design and analysis software and informatics pipelines for primary, secondary, and tertiary analysis of data generated from transcriptional, proteomic, and mult-omic assays. As a Bioinformatics Scientist, you will innovate, develop and implement novel analysis methods for different data types from sparse to large and complex datasets to support the internal development and validation of new pharmaceutical assets and the development of end-user, customer-facing data analysis and visualization for biotech customers and stakeholders. A highly motivated scientist with broad expertise and experience in bioinformatics, computational biology, transcriptomics, proteomics and multi-omics would be an ideal fit for this position.

Roles and Responsibilities

  • Prep and Process data through GATC platform based on customer or internal end user requirements.
  • Implement primary and secondary analysis tools for GATC’s assays.
  • Work with cross-disciplinary R&D teams to develop and implement new discovery and risk assessment product applications.
  • Aid in Development and implementation processes and algorithms for multi-modal datasets, scalable to very large numbers of samples.
  • Engage with external collaborators on the evaluation of beta version products and analysis of novel data.

Role Requirements

  • Degree in computational biology, bioinformatics, computer science or similar.
  • Experience analyzing complex multi-omic datasets, including human or single cell data.
  • Experience implementing, and evaluating novel bioinformatics algorithms and pipelines.
  • Experience in programming in scripting (Python or similar) and interpreted languages (R, etc).
  • Demonstrated ability to become proficient in new fields and work with interdisciplinary teams.
  • Excellent verbal/written communication and interpersonal skills with scientist and non-scientists.

Role Preferences

  • Experience using or interfacing with machine learning algorithms.
  • Experience analyzing and interpreting large-scale human or single cell datasets.
  • Experience with professional software development methods and tools in a team environment.
  • Experience in programming in scripting (Python), interpreted (R ) and compiled languages (C++ / Rust / Java).
  • Experience working with collaborators, including lab scientists on multi-omic method development.
  • Experience visualizing scientific datasets and results.
  • Experience using cloud computing environments.
  • Computational biology and bioinformatics innovation.

Personalis, Inc
Permanent
May 22, 2026

Sr. Bioinformatics Scientist - DNA Technology Development & Applied AI

$155,000 - $190,000
Fremont, CA
Hybrid

Our Mission & Technology

Personalis, Inc. is a leader in advanced genomics for precision oncology. Our signature platform, NeXT Personal, is an ultra-sensitive, tumor-informed, WGS-based (Whole-Genome Sequencing) liquid biopsy assay designed to detect minimal residual disease (MRD) and cancer recurrence.

By leveraging whole-genome sequencing of a patient's tumor and matched normal samples, NeXT Personal creates a personalized panel of up to 1,800 somatic variants. This enables the detection of circulating tumor DNA (ctDNA) at incredibly low levels—down to approximately 1-3 parts per million (PPM)—in blood samples. To enable scale, cancer research, and population sequencing, the Personalis Clinical Laboratory was built from the ground up with a strict focus on clinical accuracy, quality, big data, and operational efficiency.

Bioinformatics Senior Scientist

We are seeking a Bioinformatics Senior Scientist to join a world-class, dynamic team of bioinformatics scientists, software engineers, and laboratory scientists. In this role, you will develop, test, and apply cutting-edge cell-free and solid tumor cancer genomics products.

Working alongside our clinical evidence generation teams, you will apply our cell-free solutions to large cancer patient cohorts, profiling patient responses to therapy using our cfDNA (cell-free DNA) platforms. This position directly contributes to a new generation of genomics-based precision medicine products used by pharmaceutical partners, biotech companies, hospitals, and clinicians for therapeutic selection and patient treatment management.

Role Overview

  • Location: Fremont, California
  • Work Structure: Hybrid (Onsite required Monday & Tuesday)
  • Base Salary Range: $155,000 - $190,000 per year
  • Position Type: Full-time, Regular, Exempt

What You'll Do

Core Responsibilities

  • Platform Innovation: Design, develop, and build upon our novel cell-free platforms and products, including the NeXT Personal MRD liquid biopsy platform, with a focus on maximizing signal from complex genomic architecture.
  • Advanced Machine Learning: Explore and train Large Language Models (LLMs) and foundation models on high-throughput genomic data to enhance variant detection and extract novel biological features.
  • Data Modeling: Model and analyze large, complex genomics datasets using novel methods to generate actionable biological insights.
  • Cross-Functional Productization: Design and execute scientific projects focused on product feature feasibility, demonstrating performance and clinical advantages while collaborating cross-functionally to translate findings into production-ready software.
  • Scientific Dissemination: Publish high-impact results and present findings at major conferences in the exciting areas of cell-free DNA and cancer genomics.

What You'll Bring

Requirements & Qualifications

  • Education: Advanced degree (Ph.D.) in bioinformatics, computational biology, genomics, machine learning, or a related quantitative field.
  • Cancer Genomics Expertise: Extensive experience with cancer genomics, including a deep understanding of tumor evolution, mutational signatures, and structural variation.
  • Somatic Variant Analysis: Deep expertise in somatic mutational detection, variant calling, and false-positive filtering.
  • Liquid Biopsy Experience: Direct experience analyzing cancer liquid biopsy and cell-free DNA assays.
  • Deep Learning Chops: Strong experience utilizing and training modern deep learning architectures. A strong preference will be given to candidates who have trained or fine-tuned LLMs to decode complex biological sequences.
  • Programming Proficiency: Fluency in at least one common data science language (e.g., Python or R).
  • Execution & Communication: A proven track record of designing experimental approaches to validate complex computational findings, paired with a history of publishing and presenting scientific results.

Compensation & Total Rewards

The hiring range for this position is $155,000 to $190,000 per year. The base pay actually offered will take into account internal equity, geographic region, and the candidate’s specific job-related knowledge, skills, and experience.

In addition to base compensation, full-time regular positions include:

  • Annual performance-based bonus (or sales incentive plan)
  • Long-term incentive units (equity)
  • Full range of medical, dental, and vision insurance
  • 401(k) retirement plan with company match
  • Employee Stock Purchase Plan (ESPP)
  • Tuition reimbursement & wellness benefits
  • Sick and vacation paid time off
  • Commuter benefits & EV charging stations
  • Onsite gym access

Candidate Security & Inclusivity

Protecting Our Candidates

At Personalis, we value your security. All official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text/chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate cyber crimes targeting our community.

Equal Opportunity & Accommodations

Personalis is an Equal Opportunity Employer (Minorities/Females/Veterans/Disabilities) committed to the full inclusion of all individuals. As part of this commitment, we ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, please inform your recruiter when they contact you.

Element Biosciences
Permanent
May 22, 2026

Staff Product Owner

$144,000 - $190,000
San Diego, CA
Onsite

Our Mission

At Element Biosciences, we are passionate about our mission to empower the scientific community with more freedom and flexibility to accelerate our collective impact on humanity. We have built a highly efficient product-driven organization where employees can learn, grow, and thrive in a challenging but encouraging environment. We are committed to scientific integrity, collegiality, honesty, objectivity, and openness.  

Staff Product Owner

We're hiring a Staff Product Owner to lead software development for our multi-omic data generation instruments. You'll own the product surface where instrumentation, cloud analytics, bioinformatics, and user workflows converge.

This is a senior individual contributor (IC) role. While you won't manage direct reports, you will set direction across multiple scrum teams and act as the connective tissue between bioinformatics, hardware, chemistry, cloud, and instrument control. You should be comfortable getting hands-on prototyping, writing scripts, and running test suites—not just writing tickets.

Role Overview

  • Reporting To: Associate Director, Software Product
  • Location: San Diego, CA (Onsite)
  • Job Type: Full-time, Exempt
  • Travel: Up to 10% or as needed
  • Base Compensation: $144,000 - $190,000

What You'll Do

Essential Functions & Responsibilities

  • Backlog Ownership: Own and prioritize backlogs across multiple scrum teams; translate company initiatives into epics, user stories, and clear acceptance criteria.
  • Product Capability Definition: Define and ship product capabilities spanning instrument control, cloud analytics, ML pipelines, and emerging LLM/agent-based user workflows.
  • Cross-Functional Partnership: Partner with bioinformatics, cloud, and instrument software teams to design scalable data pipelines, analysis workflows, and control interfaces.
  • Technical Subject Matter Expert (SME): Understand the system architecture and interfaces well enough to make sound trade-off calls and unblock teams technically, not just procedurally.
  • Hands-on Validation: Prototype, write scripts, and run test suites to validate ideas, reproduce issues, and pressure-test specs before they reach engineering.
  • Requirements & Risk Management: Lead requirements gathering, requirement analysis, and risk analysis; own the Software Requirements Specification (SRS) and risk documentation.
  • User Experience (UX) Advocacy: Champion UX and human-centered design so scientists, lab techs, and bioinformaticians can seamlessly use what we ship.
  • Execution & Support: Drive cross-team coordination, surface dependencies early, keep delivery on track with minimal oversight, and support troubleshooting during development and sustaining.

What You'll Bring

Education & Experience

  • Education & Domain Expertise: Bachelor’s degree in Bioengineering, Computer Science, or a related field with 8–12+ years in life sciences software. Working knowledge of cell biology, multi-omic analysis, and DNA sequencing is required.
  • Proven Track Record: Experience shipping software that successfully spans instrumentation, cloud SaaS, and data analysis.
  • Technical Chops: Strong requirements engineering and solution architecture skills. Ability to read and write code, prototype quickly with AI tools, run/interpret test suites, and engage substantively in technical design reviews.
  • Leadership Through Influence: Experience owning product across multiple scrum teams as an IC; leading through vision and technical credibility rather than formal authority.
  • AI/ML Product Experience: Experience with traditional ML pipelines (model training, evaluation, deployment) and/or LLM/agent-based features (RAG, tool use, evals).
  • Regulated Workflows: Familiarity with regulated software workflows (e.g., IEC 62304, FDA 21 CFR Part 820, ISO 13485, or IVDR) including design controls, traceability, and verification/validation documentation for SaMD (Software as a Medical Device) or instrument software.
  • Adaptability: Strong analytical and communication skills; ability to thrive in ambiguity and fast iteration.

Our Technical Stack & Tools

  • Core Infrastructure: Go, React, MongoDB, Redis, gRPC, AWS, Ubuntu Core
  • AI Productivity Tools: Cursor, Claude

Physical Requirements

  • Ability to lift up to 20 pounds.
  • Flexibility in working hours, as this position may occasionally require customer support during non-regular business hours.

Total Rewards & Compensation

In addition to the base salary range of $144,000 - $190,000 (dependent on geographic location, qualifications, and experience), Element Biosciences offers a comprehensive benefits package:

  • Stock options
  • Discretionary annual bonus
  • No-cost health insurance plans
  • 401(k) with company match
  • Flexible paid time off (PTO)

Equal Opportunity Employment

We foster an environment such that all people are afforded the freedom to pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation, gender identity or expression, age, disability, veteran status or any other characteristics protected by law.  

Biohub
Permanent
May 22, 2026

Computational Biologist

$130,000 - $163,000
Chicago, IL
Onsite

Our Mission

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.

The Team

The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies.  

Our Vision

  • We pursue large scientific challenges that cannot be pursued in conventional environments.  
  • We enable individual investigators to pursue their riskiest and most innovative ideas.  
  • The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond.

Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.

The Opportunity

The Biohub Chicago is seeking an exceptional Computational Biologist, Spatiotemporal Multi-Omics to join our growing team. We are looking for a creative and collaborative bioinformatics researcher who is excited to build the analytical foundation for our spatiotemporal multi-omics technology platform.

What You'll Do

  • Workflow Development: Develop data analysis workflows for spatiotemporal and multi-omics datasets.
  • Data Visualization: Build visualization tools that enable exploration and interpretation of complex biological data across space and time.
  • AI & Data Integration: Integrate proteomics, metabolomics, and related datasets, and explore machine learning or transfer learning approaches to support biological discovery.
  • Cross-Functional Collaboration: Collaborate closely with experimental scientists, communicate findings clearly, and contribute to publications, presentations, and open-source software as appropriate.

What You'll Bring

Minimum Qualifications

  • Education: PhD in bioinformatics, computer science, statistics, computational biology, biomedical engineering, or a related quantitative discipline.
  • Core Experience: Minimum 2 years of experience in developing bioinformatic methods, analysis pipelines, or software tools for biological data using an appropriate programming language.
  • Domain Focus: Minimum of 1 year of experience in at least one of the following areas: spatial data analysis, multi-omics integration, or machine learning for biological applications.
  • Track Record: A strong record of research productivity, including publications, open-source contributions, or both.
  • Soft Skills: A collaborative mindset, strong communication skills, and enthusiasm for working closely with wet-lab teams.

Preferred Qualifications

  • 1+ year of experience with imaging mass spectrometry (e.g., MALDI).
  • 1+ year of experience with single-cell proteomics and/or metabolomics.
  • 1+ year of experience building visualization tools or scientific software.

Compensation & Work Environment

Salary Range

The base pay range for a new hire in this Chicago, IL role is $130,000 - $163,000.

  • New hires are typically started in the lower portion of the range to allow for growth over time.
  • Actual placement is based on job-related skills and experience evaluated during the interview process.
  • This position may be eligible to participate in our discretionary annual performance bonus program.

Hybrid Work Structure

To strengthen in-person connections and cultivate a team-oriented environment, this role is a hybrid position requiring you to be onsite for at least 60% of the working month (approximately 3 days a week). Specific in-office days are determined at the hiring manager's discretion.

Benefits for the Whole You

We offer a wide range of benefits to support the incredible people behind our work:

  • Future Planning: Generous employer match on employee 401(k) contributions.
  • Giving Back: Paid time off to volunteer at an organization of your choice.
  • Family Support: Funding for select family-forming benefits.
  • Mobility: Relocation support for employees who need assistance moving.

Our Application Philosophy: If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.  

Altos Labs
Permanent
May 22, 2026

Scientist / Senior Scientist, Computational Biology

£62,400 - £104,200
Cambridge, UK
Onsite

Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at altoslabs.com.

Our Value

Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.

Diversity at Altos

Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.  

Scientist / Senior Scientist: Computational Biology

What You Will Contribute To Altos

The ideal candidate will contribute to innovative aging and rejuvenation research efforts using large-scale omics data, collaborate across disciplines, and help develop tools that drive our scientific goals forward.

Responsibilities:

  • Design and execute computational strategies to analyze and integrate multi-omics data, including bulk and single-cell transcriptomics, epigenomics (ATACseq, ChipSeq, Cut&Run/Cut&Tag, DNA methylation), spatial transcriptomics, proteomics and related high-dimensional data sets, in support of studies in aging and rejuvenation.
  • Develop and implement robust and scalable bioinformatic pipelines, statistical models, and machine learning approaches to uncover biological insights.
  • Collaborate closely with wet-lab scientists and cross-functional computational teams to translate biological questions into analytical strategies and actionable insights.
  • Evaluate and synthesize recent scientific literature to inform the design of computational pipelines and improve research strategies.
  • Evaluate and integrate emerging computational, AI, and deep learning methodologies to enhance analytical capabilities and discovery efforts.
  • Build interactive visualization and data exploration tools to support interpretation, communication, and decision-making across teams.
  • Maintain clear, complete, and organized records of all analyses and workflows in reproducible formats (e.g., notebooks, scripts, documentation).
  • Present findings in internal lab meetings and cross-functional seminars.
  • Contribute to a collaborative and innovative research environment, including mentoring junior scientists or trainees where appropriate.

Who You Are

You are an intellectually curious scientist excited and inspired by the Altos mission of restoring cell health and resilience to reverse diseases, injury and age-related disabilities. You are keen to explore the biology of aging to develop approaches to understand and potentially reverse its effects.

You possess strong analytical skills, a passion for computational biology, and a collaborative spirit with the ability to work within and contribute to Project Teams and within a matrix structure. The ideal candidate is:

  • Self-motivated to drive and deliver on projects and goals.
  • Excited to work in a fast-paced, multidisciplinary environment.
  • Focused on professional growth and expanding their skillset and knowledge.
  • Able to communicate and explain the design, results, conclusions and the impact of their work to both scientific and nonscientific staff.
  • Able to stay up-to-date on the latest developments in their field and apply knowledge to their work.

Qualifications, Skills, Knowledge & Abilities

Minimum Qualifications

  • PhD in Life Science or Computational Biology. Level will depend on experience:
    • Scientist II: 3-5 years experience post PhD
    • Senior Scientist I: 6 years experience post PhD
  • Proven experience analyzing and integrating high-throughput omics datasets using computational and statistical approaches.
  • Proficiency in programming (e.g., Python, R) and experience working with standard bioinformatics tools and data repositories.
  • Strong foundation in statistical analysis, machine learning, or probabilistic modeling.
  • Ability to translate complex scientific questions into computational strategies and analytical frameworks.
  • Demonstrated ability to work independently and collaboratively in an interdisciplinary research environment.
  • Strong communication and problem-solving skills, with the ability to present computational analyses to both expert and non-expert audiences.
  • Track record of scientific publications in peer-reviewed journals.

Preferred Qualifications

  • Background in cellular aging, rejuvenation, cellular plasticity, and/or reprogramming biology.
  • Experience in single-cell or spatial omics, epigenomics, long-read sequencing, proteomics, and/or Ribo-seq technologies.
  • Familiarity with methods for multi-omics data integration.
  • Familiarity with machine learning, deep learning, or generative modeling approaches applied to biological data.
  • Experience developing reproducible workflows using tools such as Nextflow and cloud computing environments (e.g., AWS).
  • Previous wet-lab experience is considered a plus.

Hiring Ranges

RangeScientist II

3-5 years post PhD

£62,400 - £82,100

Senior Scientist I

6+ years post PhD

£79,200 - £104,200

Equal Opportunity Employment

We value collaboration and scientific excellence. We believe that a culture of belonging is foundational to scientific innovation and inquiry. At Altos Labs, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining an inclusive environment.

Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.  

Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/.  

Ultima Genomics
Permanent
May 20, 2026

Staff Bioinformatics Scientist, Oncology Applications

$135,000 - $170,000
Remote
Remote

Rapidly Growing Life Sciences Technology Company  

Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.  

We are looking for a highly motivated Staff Bioinformatics Scientist to join our Oncology Applications team!

As a Staff Bioinformatics Scientist, you will develop and apply computational methods for analyzing next-generation sequencing (NGS) data generated on Ultima’s platform. This role will involve building robust pipelines, developing novel algorithms, collaborating cross-functionally with molecular biology, software engineering, and product teams, and driving insights from complex genomic datasets, with a focus on growing Oncology Applications.

This position is ideal for someone who thrives in a dynamic, fast-paced environment and can effectively balance multiple high-impact projects. In addition to core R&D responsibilities, you will contribute to external-facing scientific communications and support collaborations with customers and partners.

This is a full time remote position with preferred locations in San Francisco, Boston, and Washington D.C.

How You’ll Contribute

  • Develop, optimize, and maintain scalable bioinformatics pipelines for NGS data analysis such as WGS, WES, RNA-seq, and single-cell.
  • Design and implement novel algorithms for secondary and tertiary NGS analysis tailored to Ultima’s sequencing chemistry.
  • Lead and execute multiple projects simultaneously, effectively prioritizing deliverables in alignment with evolving company goals.
  • Perform benchmarking and validation studies.
  • Analyze large-scale genomic datasets and generate actionable insights for internal R&D, product development, and external collaborators.
  • Collaborate closely with wet-lab scientists, software engineers, and product teams to translate experimental results into improved workflows and tools.
  • Support external collaborations by preparing technical analyses, reports, presentations, and data summaries for customers, partners, and conferences.
  • Contribute to scientific publications, application notes, white papers, and other external communication materials as needed.
  • Participate in customer-facing discussions to explain data analysis approaches, performance metrics, and platform capabilities.
  • Document methods clearly and communicate findings effectively to both technical and non-technical audiences.
  • Stay current with emerging technologies and advances in genomics, computational biology, machine learning, and cancer biology.
  • Other duties as assigned.

Qualifications, Skills, Knowledge & Abilities

  • PhD in Bioinformatics, Computational Biology, Genomics, Computer Science, or related field; or MS with significant industry experience.
  • PhD with 5+ years or MS with 8+ years of hands-on experience analyzing NGS data required.
  • Strong programming skills in Python and/or C++.
  • Experience with common bioinformatics and somatic variant calling tools such as BWA, minimap2, GATK, samtools.
  • Proficiency in Linux/Unix environments and workflow management systems (Nextflow, Snakemake, WDL).
  • Experience working with large datasets in cloud environments (AWS, GCP).
  • Solid understanding of genomics and cancer biology.
  • Strong statistical and data analysis skills.
  • Demonstrated ability to manage multiple concurrent priorities and deliver high-quality work under tight timelines.
  • Knowledge of machine learning approaches applied to genomics.
  • Clear and confident communicator, comfortable in external-facing settings.
  • Experience in regulated environments (CLIA, CAP) is a plus.
  • Thrive in a fast-paced, startup environment with evolving priorities.
  • Demonstrated scientific rigor and analytical thinking.
  • High ownership, accountability, and bias toward action.
  • Collaborative mindset with cross-functional agility.

Compensation & Benefits

At Ultima Genomics, your base pay is one part of your total compensation package. This role pays between $135,000 and $170,000, if performed in California, and your actual base pay will depend on your skills, qualifications, experience, and location. Please note that the compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits.

This role is also eligible for a competitive benefits package that includes: medical, dental, vision, life, and disability insurance; 401(k) retirement plan; flexible spending & health savings account; paid holidays; paid time off; employee assistance program; and other company benefits.

#LI-Remote

Equal Opportunity Employment

Ultima Genomics is proud to be an equal opportunity workplace and is an affirmative action employer. We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws.  

See also Ultima Genomics’ EEO Policy and Know Your Rights. If you have a disability or special need that requires accommodation, please let us know by contacting recruiting@ultimagen.com.

Altos Labs
Permanent
May 20, 2026

Scientist, In Vivo Genomics

$148,700 - $252,600
San Francisco Bay Area, CA
Onsite

Our Mission

Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.

For more information, see our website at altoslabs.com.

Our Value

Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.

Diversity at Altos

Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.  

What You Will Contribute To Altos

We are seeking an exceptional and versatile Scientist to join Discovery Science at Altos Labs. This role is ideal for a creative experimental scientist with deep expertise in functional genomics, in vivo biology, and/or next-generation genomics technologies who is excited to uncover new regulators of cell state, tissue resilience, and rejuvenation biology.

The successful candidate will help build and apply next-generation discovery platforms spanning in vitro and in vivo systems, with opportunities to contribute across areas such as genome-scale perturbation screening, in vivo genomics technology development, target discovery, and tissue-level functional genomics. Depending on background and interests, the successful candidate may contribute more heavily toward platform and technology development or toward mechanistic and translational biology.

We are looking for broadly capable scientists with strong technical depth, scientific creativity, and the curiosity to pursue new biological frontiers in a highly collaborative environment.

Key Responsibilities

  • Design and execute innovative research strategies to identify causal regulators of cell state, aging, regeneration, and disease biology.
  • Develop and apply functional genomics approaches, including pooled perturbation screens, CRISPR-based technologies, and other scalable discovery tools.
  • Build and apply in vivo genomics approaches to enable target discovery and mechanistic studies in physiologically relevant systems.
  • Develop robust experimental workflows connecting genetic perturbation to molecular and phenotypic readouts across cellular and animal models.
  • Apply genomic and molecular profiling methods, including transcriptome, translatome, proteome, single-cell, and spatial readouts, to uncover novel biological mechanisms.
  • Generate mechanistic hypotheses and drive validation studies using appropriate in vitro and in vivo systems.
  • Translate in vitro discoveries into in vivo systems through the design and execution of hands-on mouse studies in relevant disease models.
  • Develop, optimize, and apply in vivo delivery approaches, including viral and nucleic acid-based delivery systems such as AAV and LNP platforms.
  • Collaborate closely with computational scientists and cross-functional teams to integrate multidimensional datasets and generate actionable biological insight.
  • Lead project strategy, experimental design, execution, troubleshooting, and data interpretation.
  • Contribute to publications, patents, and broader scientific strategy.

Who You Are

  • PhD in Molecular Biology, Genetics, Genomics, Biochemistry, Bioengineering, Systems Biology, or related field, with relevant postdoctoral and/or industry experience preferred.
  • Strong track record of scientific accomplishment through publications, patents, or impactful platform development.
  • Demonstrated expertise in two or more of the following areas:
    • Functional genomics, perturbation screening, single-cell, spatial, or other next-generation genomics technologies
    • Hands-on in vivo experience with disease mouse models
    • Disease cell and mechanistic biology
    • Bioinformatics and multi-omic data analysis
  • Ability to independently lead complex research projects from concept to execution.
  • Strong analytical skills and ability to derive biological insight from multidimensional datasets.
  • Excellent written and verbal communication skills.
  • Demonstrated ability to work effectively in highly collaborative, interdisciplinary environments.
  • Scientific rigor, creativity, and comfort operating in rapidly evolving areas.

Preferred Qualifications

  • Experience with in vivo functional genomics or pooled screening approaches.
  • Expertise in single-cell sequencing, spatial genomics, ribosome profiling, lineage tracing, or other next-generation genomics methods.
  • Experience in small rodent handling, with an ability to independently design and coordinate the execution of complex in vivo studies, including drug administration, tissue harvest and processing.
  • Hands-on experience with in vivo delivery modalities including AAV, LNP, or related delivery systems.
  • Expertise in physiologically relevant model systems, including stem cell-derived systems, primary human cells, organoids, ex vivo tissue systems, or disease mouse models.
  • Experience linking large-scale discovery platforms to mechanistic follow-up and target validation.
  • Strong computational biology and bioinformatics expertise integrating transcriptomic, proteomic, translatomic, imaging, phenotypic screening, and other multi-omic datasets.
  • Background in aging biology, regeneration, fibrosis, inflammation, metabolic disease, neurodegeneration, or related therapeutic areas.
  • Experience or interest in studying novel biological mechanisms and emerging areas of biology.

The salary range for Redwood City:

  • Scientist I, Genomics: $148,700 - $190,700
  • Scientist II, Genomics: $162,700 - $208,600
  • Senior Scientist I, Genomics: $197,000 - $252,600

Exact compensation may vary based on skills, experience, and location.

#LI-NN1

For UK applicants, before submitting your application:

- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice)- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.

Equal Opportunity Employment

We value collaboration and scientific excellence.

We believe that a culture of belonging are foundational to scientific innovation and inquiry. At Altos Labs, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining an inclusive environment.

Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.  

Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/  

Deep Genomics
Permanent
May 14, 2026

Research Associate, Platform Technology

N/A
Cambridge, MA
Onsite

About Us

Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of RNA biology to identify novel drug targets, mechanisms, and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team in Toronto and Cambridge, MA is revolutionizing how new medicines are created.  

Opportunity

We are looking for a passionate and detail-oriented Research Associate to become an integral part of our Platform Technology team. This is an opportunity to contribute hands-on to an AI-driven drug discovery platform, generating the experimental data that directly informs the biological models powering our therapeutic pipeline. You will bring scientific curiosity and rigor to the bench, supporting the execution of molecular and sequencing-based assays that our computational and therapeutic teams rely on to advance program goals.

This role offers early-career professionals a meaningful foothold in a cross-functional discovery environment, with exposure to cutting-edge technologies spanning NGS workflows, liquid handling automation, and diverse RNA therapeutic modalities including ADAR editing, ASOs, siRNAs, and mRNAs. If you are eager to develop technical breadth while contributing to work that has real therapeutic impact, we encourage you to apply.

Key Responsibilities

  • Execute amplicon sequencing workflows, including NGS library preparation and targeted sequencing, under the guidance of senior team members, to support the evaluation of RNA therapeutic candidates.
  • Carry out library QC using tools such as TapeStation, Qubit, and qPCR, flagging workflow bottlenecks to ensure high-quality datasets for downstream computational analysis.
  • Operate sequencing instruments such as the Illumina NextSeq, including run setup and routine troubleshooting, with increasing independence over time.
  • Perform routine molecular biology techniques including PCR, qPCR/ddPCR, and nucleic acid extractions from a variety of cell types and tissues.
  • Assist in running automated workflows on liquid handling platforms (e.g., Hamilton STAR, Agilent Bravo, Beckman Echo) to support scaling of discovery and screening activities.
  • Maintain accurate and thorough documentation of experimental plans, results, SOPs, and troubleshooting steps within an electronic lab notebook (ELN).
  • Contribute to team meetings and share experimental results and assay updates with immediate project collaborators.

Basic Qualifications

  • BS in Molecular Biology, Genetics, Genomics, Biotechnology, Biochemistry, or a related discipline.
  • 1–3 years of relevant industry or research experience (including internships or postgraduate research).
  • Foundational knowledge of molecular and cell biology principles.
  • Hands-on exposure to amplicon sequencing or other targeted NGS workflows.
  • Experience with nucleic acid extraction, quantitation, and standard molecular biology techniques (PCR, qPCR/ddPCR, gel electrophoresis).
  • Strong attention to detail and commitment to rigorous, reproducible lab work.
  • Ability to work both independently and collaboratively in a team-oriented environment.

Preferred Qualifications

  • Proficiency with liquid handling platforms such as Hamilton, Beckman, or Bravo.
  • Working familiarity with RNA therapeutic modalities such as ADAR editing, ASOs, siRNAs, or mRNA.
  • Experience with mammalian cell culture, including transfection-based assays.
  • Prior exposure to a biotechnology, pharmaceutical, or platform-driven research environment.

Deep Genomics
Permanent
May 14, 2026

Associate Director, in vitro Pharmacology

N/A
Cambridge, MA
Onsite

About Us

Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of RNA biology to identify novel drug targets, mechanisms, and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team in Toronto and Cambridge, MA is revolutionizing how new medicines are created.  

Opportunity

The Associate Director, in vitro pharmacology will be responsible for leading the target validation function at Deep Genomics with the goal of advancing our RNA editing therapeutics portfolio. This is a leadership role with the opportunity to make a significant impact on Deep Genomics’ therapeutic pipeline. Success in this role requires the ability to lead strategically, execute tactically, and influence others in a highly matrixed and multidisciplinary team.

The ideal candidate will have direct experience in designing, executing and interpreting target validation studies for a variety of liver disease indications. Deep knowledge of a variety of in vitro liver models, relevant functional assays and genome engineering methods is essential. Direct experience with ADAR or other oligonucleotide therapeutics is highly beneficial as is experience with pooled screening approaches and laboratory automation. This role requires leadership from the bench as well as experience supervising junior scientists directly and indirectly. In addition to working closely with the therapeutic program teams, the candidate is expected to work closely with our Target Identification team to translate AI-derived target nominations into a clear action plan leading to go/no-go decisions.

As a key member of an early stage discovery team, this individual must demonstrate initiative and ownership in both scientific and strategic decisions and have an entrepreneurial mindset. Ability to pro-actively anticipate needs and independently seek solutions is a key skill, together with effective communication in all directions. This role may lead to the opportunity to manage and mentor direct reports in the future. Please note that the title is commensurate with prior experience.

Key Responsibilities

  • Lead all aspects of liver biology target validation from strategy, execution and interpretation, working with direct and indirect reports.
  • Serve as the senior liver biology subject matter expert, leading in vitro pharmacology strategy and collaborating closely with the in vivo pharmacology team to advance therapeutic programs.
  • Collaborate closely with the Target Identification team on availability, feasibility and predictive power of in vitro models and assays for new targets.
  • Present clear, data-driven go/no-go decisions on novel targets.
  • Demonstrate strong leadership, personal accountability and interpersonal skills, and capability for mentoring (direct reports and others).
  • Analyze, interpret and present data to scientists and management in internal and external venues and publish in peer-reviewed journals as appropriate.

Basic Qualifications

  • PhD in biological sciences with 6+ years of post-graduate experience in relevant roles (or equivalent) in in vitro pharmacology for the development of genetic medicines.
  • 3+ years building, managing, and leading teams to meet therapeutic program goals.
  • Direct, hands-on experience with in vitro models of liver disease and a wide array of functional assays including steatosis, inflammation and fibrosis.
  • Direct, hands-on experience with gene editing or oligonucleotide therapeutics.
  • Proven ability to work independently and cross-functionally in a fast-paced environment.
  • Ability to communicate complex data sets to key stakeholders from diverse backgrounds.
  • Strong personal qualities, including attention to detail, emotional intelligence, integrity, creativity, and a willingness to have ideas challenged by team members and to challenge them.

Preferred Qualifications

  • Experience with advanced in vitro liver models e.g. iPSC derived cells, organoids, co-culture systems.
  • Prior experience executing studies with contract research organizations.
  • Experience planning and writing regulatory packages including IND submissions.
  • Understanding of target discovery via human genetics.
  • Strong computational background or demonstrated ability to interface with computational biology teams.

What We Offer

  • A collaborative and innovative environment at the frontier of computational biology, machine learning, and drug discovery.
  • Highly competitive compensation, including meaningful stock ownership.
  • Comprehensive benefits - including health, vision, and dental coverage for employees and families, employee and family assistance program.
  • Flexible work environment - including flexible hours, extended long weekends, holiday shutdown, unlimited personal days.
  • Maternity and parental leave top-up coverage, as well as new parent paid time off.
  • Focus on learning and growth for all employees - learning and development budget & lunch and learns.
  • Facilities located in the heart of Toronto - the epicenter of machine learning and AI research and development, and in Kendall Square, Cambridge, Mass. - a global center of biotechnology and life sciences.

BillionToOne
Permanent
May 14, 2026

Process Engineering Associate II

$75,029 - $85,748
Union City, CA / Austin, TX
Onsite

Ready to redefine what's possible in molecular diagnostics?

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We seek a Process Engineering Associate II whose interests span molecular diagnostics, process optimization, and quantitative problem solving. In this role you will (1) drive process improvement and development to enhance clinical assay performance, (2) support technology transfer from R&D into our high-throughput CLIA lab, and (3) troubleshoot and identify root causes of recurring errors to enable long-term corrective actions. You will also play a key role in standing up our newly built lab in Austin, TX. You will leverage and deepen your expertise across molecular techniques, laboratory automation, and data analysis while contributing directly to category-defining NIPT assays that transform patient lives one molecule at a time. This onsite position starts at our Union City, CA laboratory and will relocate to Austin, TX in summer 2027. The Process Engineering Associate II reports to the Senior Development Scientist.

Austin Expansion Update:

We are building a brand-new state-of-the-art laboratory in Austin, Texas, expected to launch in late 2027 / early 2028, and we are looking for talented laboratory professionals who want to be part of this journey from the very beginning.

Candidates hired into this role will initially relocate to the Bay Area (Union City, CA) to train and work alongside our experienced laboratory teams. During this time (up to ~18 months), you will gain deep hands-on experience with BillionToOne’s cutting-edge molecular diagnostic workflows, quality systems, and laboratory operations before transitioning to our new Austin facility once it opens.

This is a unique opportunity to gain hands-on training with our experienced lab teams and become one of the founding members of our Austin laboratory.

Responsibilities:

  • Design, execute, and analyze wet lab experiments to improve process efficiency and assay reliability.
  • Evaluate new molecular biology techniques and technologies to enhance assay performance.
  • Perform complex manual and automated laboratory procedures (e.g. nucleic acid extraction, PCR, sequencing, reagent preparation).
  • Conduct assay validation studies to qualify new and improved assays for clinical use at both sites.
  • Build data analysis and software tools to monitor process health, surface sources of error, and accelerate troubleshooting.
  • Collaborate with the team to analyze complex data, diagnose issues, and implement solutions.
  • Support technology transfer to our new Austin, TX CLIA lab to bring the new site online.
  • Present project progress, data, and technical insights to the team and department.

Qualifications:

  • BS or MS in a relevant scientific or engineering discipline (e.g., Bioengineering, Chemical Engineering, Molecular Biology, Biochemistry, Chemistry, or Physics).
  • At least 1 year of hands-on lab research experience, including core molecular biology techniques (e.g., PCR, DNA/RNA extraction, sequencing).
  • Exceptional analytical reasoning and troubleshooting skills, with experience in data analysis (bioinformatics, statistical analysis, or similar) and comfort using modern AI tools.
  • Strong mathematical and statistical aptitude, with a process- and systems-level mindset.
  • Excellent attention to detail and clear written and verbal communication.
  • Driven, creative, and persistent, with a willingness to go above and beyond and to work both independently and collaboratively in a fast-paced environment.
  • Willingness to relocate from Union City, CA to Austin, TX in summer 2027.

Nice-to-haves:

  • Start-up experience.
  • Previous automation or clinical laboratory experience.
  • Experience with next-generation sequencing (NGS) and library preparation.
  • Experience in a cell-free DNA setting.
  • Prior experience with technology transfer, assay validation, or new lab/site standup.

Benefits And Perks:

  • Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
  • Open, transparent culture that includes weekly Town Hall meetings
  • The ability to indirectly or directly change the lives of hundreds of thousands patients
  • Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
  • Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
  • Free UNITY Complete NIPT testing for employees & spouses
  • Supplemental fertility benefits coverage
  • Retirement savings program including a 4% Company match
  • Increase paid time off with increased tenure
  • Latest and greatest hardware (laptop, lab equipment, facilities)
  • Free daily on-site lunches provided from top eateries
  • A variety of perks on campus (state of the art gym, restaurant)
  • Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $104,322 per year, including a base pay range of $75,029 - $85,748 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

For more information about how we protect your information, we encourage you to review our Privacy Policy.

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA, a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding, including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com

BillionToOne
Permanent
May 14, 2026

Process Engineering Associate II

$75,029 - $85,748
Union City, CA
Onsite

Ready to redefine what's possible in molecular diagnostics?

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We seek a Process Engineering Associate II whose interests span molecular diagnostics, process optimization, and quantitative problem solving. In this role you will (1) drive process improvement and development to enhance clinical assay performance, (2) support technology transfer from R&D into our high-throughput CLIA lab, and (3) troubleshoot and identify root causes of recurring errors to enable long-term corrective actions. You will also play a key role in standing up our newly built lab in Austin, TX. You will leverage and deepen your expertise across molecular techniques, laboratory automation, and data analysis while contributing directly to category-defining NIPT assays that transform patient lives one molecule at a time. This onsite position starts at our Union City, CA laboratory and will relocate to Austin, TX in summer 2027. The Process Engineering Associate II reports to the Senior Development Scientist.

Responsibilities:

  • Design, execute, and analyze wet lab experiments to improve process efficiency and assay reliability.
  • Evaluate new molecular biology techniques and technologies to enhance assay performance.
  • Perform complex manual and automated laboratory procedures (e.g. nucleic acid extraction, PCR, sequencing, reagent preparation).
  • Conduct assay validation studies to qualify new and improved assays for clinical use at both sites.
  • Build data analysis and software tools to monitor process health, surface sources of error, and accelerate troubleshooting.
  • Collaborate with the team to analyze complex data, diagnose issues, and implement solutions.
  • Support technology transfer to our new Austin, TX CLIA lab to bring the new site online.
  • Present project progress, data, and technical insights to the team and department.

Qualifications:

  • BS or MS in a relevant scientific or engineering discipline (e.g., Bioengineering, Chemical Engineering, Molecular Biology, Biochemistry, Chemistry, or Physics).
  • At least 1 year of hands-on lab research experience, including core molecular biology techniques (e.g., PCR, DNA/RNA extraction, sequencing).
  • Exceptional analytical reasoning and troubleshooting skills, with experience in data analysis (bioinformatics, statistical analysis, or similar) and comfort using modern AI tools.
  • Strong mathematical and statistical aptitude, with a process- and systems-level mindset.
  • Excellent attention to detail and clear written and verbal communication.
  • Driven, creative, and persistent, with a willingness to go above and beyond and to work both independently and collaboratively in a fast-paced environment.
  • Willingness to relocate from Union City, CA to Austin, TX in summer 2027.

Nice-to-haves:

  • Start-up experience.
  • Previous automation or clinical laboratory experience.
  • Experience with next-generation sequencing (NGS) and library preparation.
  • Experience in a cell-free DNA setting.
  • Prior experience with technology transfer, assay validation, or new lab/site standup.

Benefits And Perks:

  • Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
  • Open, transparent culture that includes weekly Town Hall meetings  
  • The ability to indirectly or directly change the lives of hundreds of thousands patients  
  • Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%  
  • Extremely generous Family Bonding leave for new parents (16 weeks, paid at 100%)
  • Free UNITY Complete NIPT testing for employees & spouses
  • Supplemental fertility benefits coverage
  • Retirement savings program including a 4% Company match
  • Increase paid time off with increased tenure
  • Latest and greatest hardware (laptop, lab equipment, facilities)
  • Free daily on-site lunches provided from top eateries
  • A variety of perks on campus (state of the art gym, restaurant)  
  • Free on-site EV charging (compatible with all EVs, including Tesla)  

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).  

For this position, we offer a total compensation package of $104,322 per year, including a base pay range of $75,029 - $85,748 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

For more information about how we protect your information, we encourage you to review our Privacy Policy.

BillionToOne is a next-generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell-free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete™ is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $150M+ in Annual Recurring Revenue in just five years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.

Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com

Profluent
Permanent
May 11, 2026

Senior Software Engineer, Data Platform

$170,000 — $220,000
Emeryville, California, United States
Onsite

Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

We’re looking for a Senior Software Engineer to help design, build, and scale Profluent’s data platform. This platform houses data from protein engineering campaigns, including protein designs, experimental results, partner datasets, analytical outputs, and model-ready training data. It enables rapid machine learning, biological discovery, and secure collaboration across internal and external programs.

This role is ideal for an engineer who enjoys building robust data systems: secure ingestion pipelines, well-structured warehouses, reliable data models, access controls, auditability, and infrastructure that makes complex scientific data usable at scale. You will work closely with ML, bioinformatics, and program teams to ensure Profluent’s data is organized, governed, accessible, and protected.

Responsibilities

  • Design, build, and maintain scalable data infrastructure for protein engineering campaigns, including ingestion, transformation, validation, storage, and retrieval of large scientific datasets.
  • Develop secure data pipelines for internal and partner-generated data, with strong attention to access control, data siloing, provenance, auditability, and compliance with data use restrictions.
  • Own core components of Profluent’s data warehouse and data platform, using Python, GCP, PostgreSQL, BigQuery, and related cloud-native technologies.
  • Build systems that transform raw experimental, computational, and partner data into structured, reliable, analysis-ready and model-ready datasets.
  • Establish best practices for data modeling, metadata management, data quality checks, schema evolution, versioning, and documentation.
  • Collaborate with ML engineers, computational biologists, data scientists, and program stakeholders to understand data requirements and translate them into scalable technical systems.
  • Improve engineering quality through thoughtful system design, code review, testing, CI/CD, observability, and maintainable development workflows.
  • Contribute to architectural decisions for how Profluent stores, secures, organizes, and uses data across programs and partnerships.

Qualifications

  • 5+ years of software engineering, data engineering, or data platform experience.
  • Strong proficiency in Python and modern software development practices, including git, testing, code review, CI/CD, and production deployment.
  • Experience designing and operating production data pipelines, data warehouses, and data models at scale.
  • Hands-on experience with cloud platforms, preferably GCP, and technologies such as BigQuery, PostgreSQL, object storage, workflow orchestration, and containerized services.
  • Strong understanding of data security, access control, data partitioning or siloing, audit logging, and managing sensitive or restricted datasets.
  • Experience working with complex, heterogeneous datasets and building systems that make them reliable, discoverable, and usable.
  • Ability to work independently, make sound technical decisions, and drive projects from ambiguous requirements to production systems.
  • BS, MS, or PhD in Computer Science, Engineering, Data Science, Bioinformatics, or a related technical field, or equivalent practical experience.

Preferences (but not required)

  • Experience with scientific, biological, clinical, genomic, laboratory, or high-throughput experimental data.
  • Experience managing external partner, customer, or restricted-access datasets.
  • Familiarity with data governance, lineage, metadata systems, schema registries, or data catalogs.
  • Experience with research data systems, LIMS, ELNs, Benchling, or adjacent scientific platforms.
  • Background working with ML, data science, computational biology, or cross-disciplinary technical teams.
  • Interest in learning biology, gene editing, protein design, or machine learning concepts.

What We Offer

  • High-growth opportunity with meaningful impact on the future of protein design.
  • Competitive compensation package with equity participation.
  • Hiring Salary Range: $170,000 — $220,000 USD.
  • 401(k) with a strong employer match.
  • Comprehensive benefits including health/dental/vision insurance.
  • Generous PTO policy and commitment to work-life balance.
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology.

Work Authorization RequirementApplicants must have ongoing work authorization in the United States that does not require employer sponsorship. Sponsorship will not be provided now or at any time in the future for this position.

Employment Eligibility VerificationLegal authorization to work in the United States is required. In compliance with federal law, all persons hired must verify their identity and work eligibility and complete the required employment verification form upon hire.

Element Biosciences
Permanent
May 7, 2026

Sr Engineer II, Machine Learning

$139,500 – $183,500
San Diego, CA
Onsite

At Element Biosciences, we are passionate about our mission to empower the scientific community with more freedom and flexibility to accelerate our collective impact on humanity. We have built a highly efficient product-driven organization where employees can learn, grow, and thrive in a challenging but encouraging environment. We are committed to scientific integrity, collegiality, honesty, objectivity, and openness.

We are seeking a highly skilled and motivated Senior Engineer II, Machine Learning to join our dynamic team. The ideal candidate will have experience in data science and machine learning, with a background in working with multiomic and single-cell data and/or image processing and computer vision. This role involves creating, exploring, and analyzing models, as well as applying advanced image processing techniques to drive our research and development efforts and contribute to critical programs. This role will report to Vice President, AI and will be an onsite role at our headquarters in San Diego.

If you possess the following and want to make a meaningful impact, we invite you to explore this role.

Essential Functions and Responsibilities:

  • Analyze and interpret multiomic and single-cell data to derive meaningful insights
  • Develop and implement machine learning models to support various research projects
  • Apply advanced image processing techniques to analyze biological images
  • Collaborate with cross-functional teams to design and execute experiments
  • Explore and analyze large datasets to identify patterns and trends
  • Communicate findings and insights to stakeholders through reports and presentations
  • Stay updated with the latest advancements in data science, machine learning, and biotechnology

Education and Experience:

  • Master's degree in Data Science, Bioinformatics, Computational Biology, or a related field with 5-7 years of relevant experience, or PhD with 0-3 years of experience
  • Expertise in data science and machine learning techniques is a plus
  • Proficiency in working with multiomic and single-cell data is a plus
  • Experience with advanced image processing techniques is a plus
  • Strong background in statistics is a plus
  • Proficiency in common data science tools and programming languages such as Python, PyTorch, Scikit-learn, Pandas and other relevant tools
  • Experience with cloud computing platforms (e.g., AWS)
  • Familiarity with bioinformatics tools and databases
  • Knowledge of experimental design and statistical analysis
  • Excellent problem-solving skills and attention to detail
  • Strong communication and collaboration skills

Physical Requirements:

  • Frequently moves boxes weighing up to 20 pounds

Location:

  • San Diego – on-site

Travel:

  • Domestic travel up to 10%

Job Type:

  • Full-time/Exempt

Base Compensation Pay Range:

  • $139,500 - $183,500

In addition to base compensation noted above, you will be eligible for stock options, discretionary annual bonus, no cost health insurance plans, 401k with company match, and flexible paid time off.

Please note: Base compensation will depend on multiple factors, including geographic location, qualifications, and experience.

We foster an environment such that all people are afforded the freedom to pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation, gender identity or expression, age, disability, veteran status or any other characteristics protected by law.

Profluent
Internship
April 27, 2026

Research Intern, Computational

$1,667 per week
Emeryville, California
Remote

ABOUT PROFLUENT

Profluent is an AI-first protein design company. Founded in 2022, we develop deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. Based in Emeryville, CA, we are backed by leading investors including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

POSITION SUMMARY:

Our generative models learn the blueprint of life by modeling large-scale evolutionary data, enabling us to engineer and write biology in unprecedented ways. We are seeking a passionate Computational Research Intern to join moonshot projects at the intersection of bioinformatics and machine learning. This is a rare opportunity to tackle open-ended scientific and engineering challenges with direct potential for high-impact publications and real-world applications in synthetic biology and protein engineering.

RESPONSIBILITIES:

  • Design and implement computational approaches to advance cutting-edge research in bioinformatics and machine learning.
  • Analyze large-scale genomic and protein datasets to uncover new biological insights and capabilities.
  • Collaborate closely with scientists and engineers across machine learning, protein engineering, and biology teams.
  • Document and present research findings internally, with the potential to publish in leading journals and conferences.

QUALIFICATIONS:

  • Enrolled in a BS, MS, or PhD program in Bioinformatics, Computational Biology, Computer Science, Statistics, or a related quantitative field.
  • Strong programming skills in Python and familiarity with scientific computing libraries (e.g., NumPy, pandas, Jupyter).
  • Experience in one or more of the following: machine learning, large-scale data analysis, genomics, or protein bioinformatics.
  • Excellent problem-solving skills, scientific curiosity, and ability to work both independently and collaboratively.

INTERNSHIP DETAILS:

  • Typical duration: 12 weeks, with flexible start dates.
  • Hybrid: 2 - 3 days on-site per week in our Emeryville, CA headquarters.
  • Salary: $1,667 per week.
  • Opportunity to publish your work and make a lasting impact in computational biology and AI-driven protein design.

WHAT WE OFFER:

  • Work on moonshot projects at the frontier of AI and biology.
  • Mentorship from leading experts in bioinformatics, machine learning, and synthetic biology.
  • A dynamic, mission-driven environment with the resources of a fast-growing, well-funded startup.
  • Competitive internship compensation and benefits.

Profluent
Permanent
April 27, 2026

Lead Bioinformatics Scientist, NGS

$160,000 – $230,000
Emeryville, California
Hybrid

Computational Scientist (NGS Analysis) – Profluent

Profluent is an AI-first protein design company founded in 2022. Based in Emeryville, CA, the company develops deep generative models to design and validate novel, functional proteins to revolutionize biomedicine. They are backed by leading investors, including Altimeter Capital, Bezos Expeditions, Spark Capital, Insight Partners, Air Street Capital, AIX Ventures, and Convergent Ventures, and have raised over $150M to date.

Position Summary

We are seeking an experienced computational scientist to lead the design, development, and operation of the NGS analysis platform that powers Profluent’s gene editing and protein design programs. This role sits at the intersection of computational biology, software engineering, and experimental biology to build scalable systems for extracting actionable insights from large-scale sequencing data. You will architect core bioinformatics infrastructure, define analytical strategy, and collaborate closely with experimental and ML teams to accelerate design-build-test-learn cycles. You will also mentor team members, promote software engineering best practices, and help shape the future of Profluent’s computational biology capabilities.

Responsibilities

  • Leadership: Lead the design and implementation of scalable NGS analysis pipelines supporting gene editing and protein engineering workflows.
  • Visualization: Develop clear, intuitive visualizations and reports to communicate sequencing results and biological insights.
  • Infrastructure: Manage cloud-based compute environments and data systems for large-scale datasets.
  • Cross-Functional Collaboration: Partner with biology teams to analyze results, troubleshoot, and optimize experimental design.
  • Data Integration: Collaborate with machine learning teams to curate data for model training.
  • Engineering Standards: Establish best practices for code review, testing, and CI/CD in computational workflows.
  • Mentorship: Mentor junior scientists and foster a culture of rigor, reproducibility, and innovation.

Qualifications

  • Education: PhD or MS in Bioinformatics, Computational Biology, Computer Science, or a related quantitative field.
  • Experience: 5+ years of experience analyzing NGS datasets (e.g., amplicon sequencing, high-throughput editing, or screening experiments).
  • Programming: Strong programming skills in Python (pandas, numpy, biopython, etc.).
  • Orchestration: Expertise with workflow orchestration tools (Nextflow, Snakemake) and cloud environments (GCP, AWS).
  • Infrastructure: Experience with containerization (Docker, Kubernetes) and scalable compute infrastructure.
  • Technical Proficiency: Deep understanding of Linux, git-based version control, and software engineering best practices.
  • Analysis: Proven ability to transform complex sequencing data into actionable biological insights.

Preferences (Not Required)

  • Experience with gene editing technologies (CRISPR, base or prime editing; strongly preferred).
  • Familiarity with SQL and data modeling for biological or experimental data.
  • Experience with LIMS platforms (e.g., Benchling) and lab data integration.
  • Track record of developing production-quality scientific software or open-source bioinformatics tools.

What We Offer

  • High-growth opportunity with meaningful impact on the future of protein design.
  • Competitive compensation package with equity participation.
  • Comprehensive benefits including health, dental, and vision insurance.
  • Generous PTO policy and commitment to work-life balance.
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology.

Compensation

  • Hiring Salary Range: $160,000 – $230,000 USD.

Profluent Bio, Inc. is an equal opportunity employer. Legal authorization to work in the United States is required. Applicants must have ongoing work authorization in the United States that does not require employer sponsorship. Sponsorship will not be provided now or at any time in the future for this position.

Retro
Permanent
April 27, 2026

Scientist, Hematopoiesis (iPSCs)

N/A
Redwood City, CA
Onsite

Retro Biosciences

About RetroRetro develops therapies for diseases driven by the biology of aging. We focus on cellular reprogramming and autophagy to broadly improve tissue function by targeting mechanisms of aging with the ultimate aim of adding 10 years to healthy human lifespan.

We’re building a mission-driven team of accomplished and kind individuals who embrace our startup culture of rapid iteration, transparency, and versatility.

We are hiring a new member of the HSC Therapeutics team who will bring deep expertise in hematopoiesis. In this role, you will focus on process optimization and development to help us create scalable differentiation protocols.

About you:You’re eager to learn and approach work with a “can-do” attitude and a hands-on nature. You take pride in working at the highest standard, continuously optimizing research practices for both high speed and accuracy. You value being organized and detail-oriented. Bringing a clear, transparent communication style, you collaborate effectively with specialists of various backgrounds (bench and computational biologist, quality control scientists, operational and logistic specialists). You are adaptable and able to iterate quickly and reprioritize based on a mission > team > self hierarchy. You’re motivated to work on the forefront of science and help us extend healthy lifespan!

In this role you will:

  • Adapt differentiation protocol to large-scale production in bioreactors and optimize banking of final product for clinical use.
  • Optimize differentiation process for reproducible and predictable cell output.
  • Contribute to the full process of producing a high-quality iHSC product out of iPSCs: maintain iPSCs, prepare and change media throughout differentiation, analyze cells using flow cytometry, and formulate iHSCs.
  • Transfer differentiation and formulation protocols to the GMP environment.
  • Assist in processing mouse tissues and performing flow cytometry to characterize cell function.
  • Work collaboratively across Retro teams such as Technical In-Vivo, Computational Biology, Automation, and Quality and Analytics.
  • Be part of a rotational weekend work schedule.

You might thrive in this role if you:

  • Have a Bachelor’s or Master’s degree in Biology or a relevant field and 4+ or 6+ years of relevant experience in industry, respectively, or a Ph.D. in Cell Biology, Molecular Biology, or related discipline.
  • Learn quickly and establish and follow protocols precisely.
  • Your deepest expertise is in hematopoiesis.
  • Have 2+ years of experience in differentiating iPSCs into immune cells.
  • Enjoy standardizing lab practices and establishing highly reproducible protocols.
  • Have 2+ years of experience with cell characterization using flow cytometry.
  • Have excellent note-taking skills and take pride in maintaining detailed ELN.
  • Proficient in designing and coordinating projects across multiple parties.
  • Proficient in communicating results of experiments.

It’s a bonus if you:

  • Had exposure to the GMP environment and participated in IND filings.
  • Have experience with process development and scaling cell therapies in bioreactors.

Galatea Bio
Permanent
April 27, 2026

Clinical Data and Project Manager

N/A
Miami, Florida
Onsite

Who We Are

Galatea Bio is an innovative, venture backed biotechnology company with a mission to advance precision health for all. Founded by pioneers in the human genetics and bioinformatics industry, we identified a major gap in the way underrepresented communities are included in and derive benefit from advances in precision health, such as the development of new tests and cures. The last 20 years have seen an explosion of genetic information and data. New technological advances have made it faster and less expensive to understand the human genomes but most of those resources have focused on northern European communities. The mission of Galatea Bio is to channel the diversity of the world into advancing genomic medicine for the benefit of all. Leveraging clinical-grade biobanking, research and clinical genomics, and best-in-class ancestry and genome annotation algorithms, we will better understand the genetic architecture of underserved populations and power the next generation of precision medicine studies while maintaining an uncompromising commitment to ethical research. Read more at www.galatea.bio.

About this opportunity

As our Project Manager you will lead the launch of a new research project, from scratch, ensuring the achievement of milestones and deliverables in a timely manner. Parallel to launch you will also develop our internal knowledge base and establish the infrastructure for future research projects at Galatea Bio; from IRB approvals, to tooling, to documentation and tracking. You will be the liaison between study participants, research staff, and all stakeholders involved with ensuring a successful study. In this role you will report to the VP of Clinical Testing & Quality Control.

Responsibilities

  • As your first initiative, you will be responsible for monitoring sample and data flow for two new Miami-based studies and coordinating with our ex-US team for an ongoing study in Colombia.
  • As an integral component of your project plan, you will also scope out potential project risks, and preemptively incorporate efforts to minimize issues effectively.
  • Coordinate resources, timelines, and deliverables for both short term and long term objectives.
  • Collaborate with our recruitment team to perform intake assessments and data collection / management.
  • Maintain an overview, ensuring availability of inventory equipment and supplies at given research sites.
  • Enhance and take ownership of our repository of study files, including regulatory binders, source documentation, and other relevant material.
  • Conduct regular updates on project milestones and progressive performance of your studies, including patient onboarding rates, recontacting rates, and data deposition rates.

What you bring:

  • At least 5 years of clinical research coordination experience and/or recruitment of individuals into research studies.
  • Strong planning and project management skills, with a natural ability to influence collaboration
  • Practical experience within a Contract Research Organization or as part of a multi-site Clinical Study.
  • Excellent organization and communication skills, with high attention to detail.
  • Proficient with clinical study software, such as REDCap, ClinCapture, Castor, viedoc, etc.
  • Bilingual in Spanish is required
  • CITI certifications and practical experience with IRBs are a major plus.

Benefits

  • Competitive Salary
  • Eligibility for annual bonus
  • Stock Options
  • Health benefits, including dental and vision plans
  • 401k plan with company match
  • Flexible PTO
  • Diverse, inspiring, and highly academic colleagues

Deep Genomics
Permanent
April 27, 2026

Senior MLOps Engineer

N/A
Toronto, Ontario
Onsite

Senior MLOps Engineer - Deep Genomics

Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of RNA biology to identify novel drug targets, mechanisms, and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team in Toronto and Cambridge, MA is revolutionizing how new medicines are created.

The Opportunity

Join us in building the future of AI-driven drug discovery. In this role, you will own and evolve the infrastructure that powers our ML pipelines—from cloud environments and CI/CD systems to workflow orchestration and model deployment. You will work closely with ML scientists, bioinformaticians, and software engineers to keep our platform reliable, reproducible, and scalable.

Key Responsibilities

  • Infrastructure: Maintain and improve cloud infrastructure (GCP) using Infrastructure-as-Code tools (Terraform).
  • Governance: Manage IAM, RBAC, and permission policies across cloud environments.
  • CI/CD: Own and evolve pipelines (CircleCI, GitHub Actions) and ensure best practices are followed.
  • Orchestration: Administer and support workflow orchestration platforms (e.g., Seqera/Nextflow, Argo, Kubeflow).
  • ML Ops: Operate and configure ML experiment tracking and registry tooling (e.g., W&B, MLflow).
  • Containerization: Build and maintain containerized environments (Docker) and manage Kubernetes clusters.
  • Hardware: Manage GPU resources—provisioning, scheduling, and debugging hardware and driver issues.
  • Tooling: Write and maintain Python tooling, scripts, and integrations that support ML infrastructure.
  • Deployment: Deploy ML models to production environments and monitor their performance.

Qualifications

Basic Qualifications

  • Experience: 4+ years of experience operating production infrastructure.
  • Cloud & IaC: Proficiency with cloud platforms (GCP preferred; AWS/Azure acceptable) and Infrastructure-as-Code (Terraform).
  • Containers: Extensive hands-on experience with Kubernetes and Docker.
  • CI/CD: Solid background in systems like CircleCI or GitHub Actions.
  • GPU Management: Experience provisioning, debugging, and managing drivers for GPU compute.
  • Programming: Strong Python programming skills; familiarity with package and environment management (e.g., pip, conda, pixi).
  • Soft Skills: Self-motivated problem solver with excellent communication skills.

Preferred Qualifications

  • ML Familiarity: Understanding of ML frameworks (e.g., PyTorch), workflows (training/inference), and the model lifecycle.
  • MLOps Tooling: Familiarity with tools like W&B, Ray, or VertexAI, and distributed compute patterns.
  • Kubernetes: Knowledge of K8s CRDs and batch/gang schedulers (e.g., Volcano, Kueue).
  • Data: Experience with large-scale datasets, storage, and versioning.
  • Domain Knowledge: Interest or experience in biology and/or machine learning science.
  • Environment: Experience working directly with scientists in an interdisciplinary setting, and familiarity with data compliance (HIPAA, SOC 2).
  • Startup: Previous startup experience.

What We Offer

  • Impact: A collaborative and innovative environment at the frontier of computational biology, machine learning, and drug discovery.
  • Compensation: Highly competitive compensation, including meaningful stock ownership.
  • Benefits: Comprehensive health, vision, and dental coverage for employees and families; employee and family assistance programs.
  • Flexibility: Flexible hours, extended long weekends, holiday shutdown, and unlimited personal days.
  • Family Support: Maternity and parental leave top-up coverage, as well as new parent paid time off.
  • Growth: Dedicated learning and development budget, plus regular "lunch and learns."
  • Locations: Modern facilities in the heart of Toronto (an epicenter of ML/AI research) and Kendall Square, Cambridge, MA (a global center of biotech).

Ultima Genomics
Permanent
April 27, 2026

Bioinformatics Researcher II

N/A
Tel Aviv District, Israel
Onsite

Bioinformatics Researcher II – Ultima Genomics

About Ultima GenomicsUltima Genomics is a rapidly growing company developing ground-breaking genomics technologies. Their mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. They have developed a foundational new approach to sequencing at scale that overcomes the limitations of current high-cost technologies. The company is well-funded, having raised approximately $600 million from global top-tier investors. Their diverse team includes entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, and operations leaders.

Role Overview

The R&D team in Israel is looking for a highly motivated Bioinformatics Researcher II to join their team. You will design and execute analyses on Ultima sequencing data, develop computational methods, and build scalable pipelines that turn raw data into clear biological insights, working at the intersection of biology, computing, and AI.

Responsibilities

  • Build and run pipelines: Design and execute analysis pipelines on sequencing data in a cloud-based environment.
  • Work across teams: Collaborate with lab scientists, bioinformatic scientists, data scientists, and clinical partners to define requirements, provide analysis support, and influence the direction of the scientific platform.
  • Develop and adapt methods: Create new algorithms and apply state-of-the-art approaches to turn high-throughput data into biological insights.
  • Ensure rigor: Use quantitative and computational methods to validate results and strengthen the impact of findings.

Qualifications

  • Education: MS or PhD in Computational Biology, Bioinformatics, Computer Science, or a related discipline.
  • Experience: 3+ years of relevant industry or academic experience in a hands-on bioinformatics role is preferred.
  • NGS Proficiency: Demonstrated experience analyzing and interpreting large-scale Next Generation Sequencing (NGS) datasets such as WGS, WES, and RNA-seq.
  • Programming: Expert proficiency in Python for complex data analysis and proficiency in UNIX.
  • Quantitative Skills: A strong foundation in statistics and quantitative analyses.
  • Software Development: Proficiency with best practices, including version control with Git, containerization with Docker, and unit testing.
  • Specialization: Deep expertise in a specific area of genomics, such as somatic variant calling, structural variation, or single-cell analysis.
  • Cloud & Workflows: Hands-on experience deploying and managing bioinformatics workflows in a cloud environment (AWS/GCP) using tools such as WDL, Nextflow, or Snakemake.

Ultima Genomics is an equal opportunity workplace and an affirmative action employer.

GenBio AI
Permanent
March 22, 2026

Bioinformatics Data Engineer

N/A
Abu Dhabi
Onsite

GenBio AI develops multiscale foundation models to decode and simulate human biology. Our team is accelerating towards an ambitious future where scientists can unlock humanity's biggest challenges in drug discovery, healthcare, and fundamental research with AIDO (AI-Driven Digital Organism): a unified framework for predicting, simulating, and programming biology across all scales. The foundation of this vision begins today as we engineer the virtual cell to model and simulate the fundamental unit of life.

This vision has brought together a talent-dense group of product-minded researchers and engineers dedicated to bringing it to reality. Our team prides itself on our strong engineering culture and highly interdisciplinary and collaborative approach. We are based in Palo Alto, with satellite offices in Paris and Abu Dhabi.

As our data ingestion needs grow, we are looking for a Bioinformatics Data Engineer to act as the crucial bridge between raw biological data and our scalable infrastructure. Reporting to the Data Engineering Lead, you will leverage your deep biological domain expertise to build the initial scripts and processing logic for complex datasets, ensuring they are primed for large-scale foundation model training.

Responsibilities

  • Source & Acquire Biological Data - Identify, evaluate, and obtain high-quality bioinformatics datasets from public and partner sources (e.g., NCBI, PubChem, ENCODE, UniProt etc.) to support research and model development initiatives.
  • Deeply Understand Complex Datasets - Develop a comprehensive understanding of biological datasets, including data structures, schemas, metadata standards, entity relationships, and underlying biological context to ensure accurate interpretation and usage.
  • Design & Implement Data Processing Pipelines - Develop robust preprocessing scripts and scalable data transformation workflows using Python, R, and relevant Tools. Leverage AI-assisted tools where appropriate to process, clean, normalize, and integrate complex biological data for foundation model training.
  • Structure & Standardize Biological Data - Organize heterogeneous datasets into well-defined, interoperable formats aligned with internal infrastructure requirements and downstream AI training pipelines.
  • Bioinformatics Data Analysis - Perform exploratory and statistical analysis of genomic, transcriptomic, proteomic, and other multi-omics datasets to assess data quality, uncover biological patterns, and generate insights that inform model development. Apply appropriate computational and statistical methods to validate assumptions and support downstream AI training and evaluation.
  • Build Data Products - Create production-ready data assets, including standardized datasets, curated releases, dashboards, analytical reports, and technical documentation to enable efficient research and model evaluation.
  • Ensure Data Quality & FAIR Compliance - Curate, annotate, validate, and standardize public and partner datasets in alignment with FAIR (Findable, Accessible, Interoperable, Reusable) principles, ensuring long-term usability and reproducibility.
  • Collaborate Cross-Functionally - Partner closely with research scientists and ML engineers to translate biological research needs into scalable data engineering solutions that support AI model training and evaluation.
  • Knowledge Sharing & Documentation - Contribute domain expertise by documenting data methodologies, maintaining clear technical documentation, and sharing biological data insights across teams.

Qualifications

  • Educational Background: Bachelor’s or Master’s degree in Bioinformatics, Computational Biology, Computer Science, or a related field with a heavy focus on the life sciences.
  • Biological Data: Deep, hands-on familiarity with multiple biomedical data modalities (e.g., genomics, transcriptomics, spatial omics, protein structure, biomedical imaging, clinical/phenotypic data, etc.).
  • Biological Tools: Familiar with Bioconda, Biopython, Bioconductor, samtools, bamtools, bcftools, gffutils etc.
  • Scripting & Tooling: Strong programming skills in Python (Pandas, NumPy) and proficiency with standard bioinformatics workflow managers and tools (e.g., Ray, Kubeflow).
  • Engineering Handoff: Experience writing clean, modular code that can be easily picked up by core data engineers for optimization in cloud environments (AWS/GCP/HF) and containerized setups (Docker).
  • AI/ML Awareness: A solid understanding of machine learning workflows and how biological data must be formatted and batched for deep learning frameworks (e.g., PyTorch).

Ultima Genomics
Permanent
March 22, 2026

Senior Software and Algorithm Engineer

N/A
Tel Aviv District, Israel
N/A

Rapidly Growing Life Sciences Technology Company

Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.

We are looking for a highly motivated Senior Software and Algorithm Engineer to join our team!

As a Senior Software and Algorithm Engineer you will help us with implementing innovative bioinformatics algorithms and extracting more insights from the data our product generates.

How You’ll Contribute

  • Participate in the architecture and software design of bioinformatics solutions
  • Implement bioinformatic algorithms in an efficient, reusable and manageable C/C++ code
  • Learn in-depth the required algorithms, analyze their complexity and find/invent ways to implement them in the most efficient way possible
  • Work on existing and on new pipeline infrastructures, both on-prem and at cloud environments
  • Manage performance tuning, integrations, testing and bug fixing

Qualifications, Skills, Knowledge & Abilities

  • BS degree in Electrical Engineering, Software Engineering, Computer Science or equivalent
    • MS degree or other advanced studies in above fields is a plus
  • 5+ years of experience working as a senior software engineer
  • 5+ years of experience working with C/C++
  • Experience in implementing analytical algorithms in C/C++, similar language or lower-level code
    • Experience with bioinformatics algorithms is a plus
  • Familiarity with other programing languages: Python, Java, R, Rust
  • Familiarity with public cloud environments (AWS, GCP, Azure), Containers (docker) and Orchestrators (K8S)
  • Knowledge of workflow management systems (e.g., Prefect, Airflow, Luigi)
    • Familiarity with pipeline languages such as WDL, Nextflow or Snakemake is a plus

Ultima Genomics is proud to be an equal opportunity workplace and is an affirmative action employer. We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws. If you have a disability or special need that requires accommodation, please let us know by contacting recruiting@ultimagen.com.

Ginkgo Bioworks Inc.
Permanent
March 22, 2026

Senior Software Engineer, Full Stack

$134,300.00 - $189,900.00
Boston, Massachusetts
Onsite

Our mission is to make biology easier to engineer. Ginkgo is constructing, editing, and redesigning the living world in order to answer the globe’s growing challenges in health, energy, food, materials, and more. Our bioengineers make use of an in-house automated foundry for designing and building new organisms.

This role strongly prefers candidates located in the Boston area with the ability to regularly commute to our Seaport headquarters.

Due to the nature of this role, candidates should expect to support U.S. Government customers. Candidates must have the ability to obtain and maintain a U.S. security clearance per business requirements. In connection therewith, candidates must be willing to undergo a background investigation and meet eligibility requirements. Clearance sponsorship will be available.

Candidates who currently hold an active or recently inactive U.S. Government security clearance are encouraged to apply.

Ginkgo Biosecurity is building next-generation biosecurity infrastructure to help governments and partners detect, attribute, and deter biological threats. Our mission extends across public health, national security, and global defense, ensuring nations can rapidly identify dangerous pathogens, understand where threats originate, and respond with confidence.

We are seeking a Senior Full-Stack Software Engineer to join the Biosecurity engineering team. This role is ideal for someone who thrives in cross-disciplinary environments and is excited to build production software that directly supports biosecurity, epidemiology, and biological data workflows. We are looking for an engineer who is not only a technical expert but also a forward-thinker who embraces AI-augmented development and maintains a 'deploy-with-confidence' culture through rigorous CI/CD and automated testing.

You will work across the stack—from backend services and data pipelines to user-facing web applications—building reliable, scalable systems that turn complex biological data into actionable insights.

Responsibilities

  • Develop high-performance full-stack applications that translate complex biological data and operational needs into intuitive software using Python and modern JavaScript frameworks.
  • Champion an AI-first mindset, leveraging generative AI tools and LLM-based assistants to accelerate feature development, optimize code quality, and automate routine engineering tasks.
  • Collaborate with cross-functional domain experts to architect and operate on biological datasets (genomic, diagnostic, or epidemiological), ensuring that surveillance workflows maintain high standards for data integrity, provenance, and security.
  • Influence the technical roadmap and long-term evolution of the Biosecurity platform, identifying and mitigating technical debt and architectural bottlenecks before they impact delivery.
  • Design and implement robust CI/CD pipelines where automated unit, integration, and security testing are treated as mandatory gates for every code deployment.
  • Drive engineering excellence by leading technical design reviews and providing critical feedback on software modularity, while upholding rigorous standards for documentation, observability, and long-term maintainability.
  • Support production systems by monitoring performance, troubleshooting issues, and continuously improving reliability, including on-call support and triage in off hours.

Minimum Requirements

  • 6-8+ years of professional software engineering experience, with significant full-stack development work, including ownership of complex systems and cross-team technical initiatives.
  • Strong proficiency in Python for backend development (our primary programming language).
  • Experience building and consuming APIs (REST and/or GraphQL).
  • Experience developing modern web frontends using JavaScript/TypeScript and frameworks such as React.
  • Demonstrated ability to integrate AI-assisted development tools (e.g., GitHub Copilot, Cursor, or similar) into daily workflows to increase productivity and code reliability.
  • Proven experience collaborating with domain experts (scientific, operations, product, etc) to translate complex biological data (genomic, diagnostic, or epidemiological) into robust software solutions and actionable insights.
  • Solid grounding in software engineering fundamentals: data structures, system design, version control, and modern CI/CD patterns for automated testing and deployment.

Preferred Capabilities and Experience

  • Prior experience in bioinformatics, computational biology, public health, or a related domain.
  • Familiarity with cloud infrastructure (e.g., AWS) and containerized environments (Docker, Kubernetes).
  • Experience with data pipelines, workflow orchestration, or analytics platforms.
  • Exposure to regulated or sensitive-data environments (e.g., HIPAA, public health data).
  • Demonstrate high levels of ownership and independent execution.
  • Comfort working in fast-moving, ambiguous problem spaces where requirements evolve.
  • Flexibility and willingness to work on the highest priority needs of the business.

The base salary range for this role is $134,300.00 - $189,900.00. Actual pay within this range will depend on a candidate's skills, expertise, and experience. We also offer company stock awards, a comprehensive benefits package including medical, dental & vision coverage, health spending accounts, voluntary benefits, leave of absence policies, 401(k) program with employer contribution, 8 paid holidays in addition to a full-week winter shutdown and unlimited Paid Time Off policy.

It is the policy of Ginkgo Bioworks to provide equal employment opportunities to all employees, employment applicants, and EOE disability/vet.

Privacy NoticeI understand that I am applying for employment with Ginkgo Bioworks and am being asked to provide information in connection with my application. I further understand that Ginkgo gathers this information through a third-party service provider and that Ginkgo may also use other service providers to assist in the application process. Ginkgo may share my information with such third-party service providers in connection with my application and for the start of employment. Ginkgo will treat my information in accordance with Ginkgo's Privacy Policy. By submitting this job application, I am acknowledging that I have reviewed and agree to Ginkgo's Privacy Policy as well as the privacy policies of the third-party service providers used by Ginkgo's associated with the application process.

Biohub
Permanent
March 22, 2026

Staff Data Scientist, Genomics

$214,000 - $294,800
Redwood City, CA (Hybrid)
Hybrid

Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.

The Team

Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology — developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide.

Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools.

The Opportunity

This is an opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science. You’ll work alongside leading experts in AI and biology, with the resources and mandate to tackle some of the most important questions in human health — advancing frontier AI research, accelerating engineering velocity, connecting rich biological data to AI systems, enabling reliable compute across environments, and translating models and data into usable, scalable applications that drive scientific impact.

The role is part of the Data team, which focuses on owning the strategy, sourcing and implementation for data supporting AI research and development. We're a small team with significant resources and long time horizons. Our goal is to maximize the speed, agility, and capability of biological AI research by connecting public data resources and Biohub's experimental platforms to AI systems.

The data that trains biological frontier models comes in dozens of modalities (sequences, images, spatial coordinates, time series, molecular structures, metadata, publication artifacts) each with its own noise characteristics, biases, and information content. The question of how to represent this data for learning is one of the most important open problems in biological AI.

We’re looking for a data scientist with deep expertise in genomics (e.g., bulk and single-cell sequencing, functional genomics, CRISPR screens), who thinks creatively about data representation and tokenization, and can translate that thinking into novel training architectures. You’ll work across experimental, computational, and AI teams to build scalable, interpretable genomic data systems that power next-generation biological models and accelerate human health discovery.

What You'll Do

  • Set technical vision and strategy for the design of data representations and tokenization strategies for diverse biological data types that enable novel model architectures.
  • Define data standards and quality metrics that enable reliable cross-dataset integration and model-ready data products.
  • Develop and validate approaches for combining heterogeneous data modalities into unified training frameworks, designing for robustness to noise, bias, and batch effects.
  • Evaluate how representation choices impact model performance, identifying which biological signals are captured or lost and iterating to improve.
  • Partner deeply with ML engineers and AI researchers to co-design datasets and feedback loops that optimize model training, evaluation, and generalization.
  • Lead cross-functional initiatives spanning data engineering, infrastructure, science, and product, aligning technical execution with long-term scientific goals.
  • Identify and drive new data acquisition and generation opportunities, from external collaborations to internal experimental pipelines.
  • Serve as a technical mentor and leader, raising the bar for data science and ML rigor across the organization.

What You'll Bring

  • PhD in computational biology, bioinformatics, or a quantitative biological field.
  • 8+ years of experience working with large-scale biological datasets (genomics, epigenomics, transcriptomics, proteomics, or multi-omics), including ownership of end-to-end data products.
  • Deep understanding of biological measurement types (sequencing, imaging, proteomics, or related), their underlying data characteristics, and how to transform raw data into AI-ready datasets.
  • Experience designing data representations or feature engineering for machine learning in biomedical contexts.
  • Strong computational skills (Python, scientific computing libraries); demonstrated ability to design robust, extensible data architectures and to evolve standards in fast-moving scientific domains.
  • Strong expertise in machine learning and statistical modeling, with experience applying these methods to data quality assessment, automation, or decision-making systems.
  • Familiarity with modern ML architectures (transformers, diffusion models, or similar) and how data representation choices affect learning.
  • Excellent communication skills, with the ability to translate between biology, ML, and engineering audiences.
  • Creativity, curiosity, scientific judgment, and a willingness to engage deeply with new biological domains and emerging AI paradigms.

Compensation

The Redwood City, CA base pay range for a new hire in this role is $214,000 - $294,800. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

Better Together

As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager.

Benefits for the Whole You

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

  • Generous employer match on employee 401(k) contributions.
  • Paid time off to volunteer at an organization of your choice.
  • Funding for select family-forming benefits.
  • Relocation support for employees who need assistance moving.

Biohub
Permanent
March 22, 2026

Staff Data Scientist, Imaging

$214,000 - $294,800
Redwood City, CA (Hybrid)
Hybrid

Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.

The Team

Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide.

Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools.

The Opportunity

This role is part of the Data team, which focuses on owning the strategy, sourcing and implementation for data supporting AI research and development. Our goal is to maximize the speed, agility, and capability of biological AI research by connecting public data resources and Biohub's experimental platforms to AI systems.

The data that trains biological frontier models comes in dozens of modalities—sequences, images, spatial coordinates, time series, molecular structures, metadata, preprints and published papers—each with its own noise characteristics, biases, and information content. The question of how to represent this data for learning is one of the most important open problems in biological AI.

You will operate with broad scope and high autonomy, influencing roadmap decisions across teams while mentoring senior individual contributors. Success in this role means scaling data systems that are not only large, but adaptive, interpretable, and scientifically grounded, accelerating progress toward robust biological frontier models and ultimately advancing human health.

We're looking for data scientists who can work at this frontier: people who understand biological measurement deeply, think creatively about data representations and tokenization strategies, and can translate that thinking into novel training architectures. You'll work directly with experimental and computational scientists, data scientists and AI researchers to define what the models see and how they see it, and data engineers to make this work at scale. This is a role for someone who wants to invent the methods that make biological frontier models possible.

What You'll Do

  • Design data representations and tokenization strategies for imaging data that enable novel model architectures
  • Coordinate Experimental, Data Science, Data Engineering and AI Research teams to translate biological structure into learnable representations—defining priorities and appropriate structures for metadata and data that information models can access and consume
  • Work across those teams to guide data acquisition priorities, define quality criteria, and assess external datasets from a representation perspective
  • Develop and validate approaches for combining heterogeneous data modalities into unified training frameworks, designing for robustness to noise, bias, and batch effects
  • Evaluate how representation choices impact model performance, identifying which biological signals are captured or lost and iterating to improve

What You'll Bring

  • PhD in computational biology, bioinformatics, or a quantitative biological field
  • Experience with tokenization strategies for non-text data (images, sequences, graphs, time series)
  • Track record of novel methodological contributions (publications, open-source tools, or production systems)
  • Familiarity with biological foundation models (ESM, scGPT, or similar)
  • Deep understanding of imaging data, their underlying data characteristics, and how to transform raw data into ai-ready datasets
  • Experience designing data representations or feature engineering for machine learning, ideally in scientific or biological contexts
  • Familiarity with modern ML architectures (transformers, diffusion models, or similar) and how data representation choices affect learning
  • Strong computational skills (Python, scientific computing libraries); comfort working with large-scale datasets
  • Creative, first-principles thinking about how to structure data for learning

Compensation

The Redwood City, CA base pay range for a new hire in this role is $214,000 - $294,800. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

Better Together

As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

Benefits for the Whole You

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

  • Provides a generous employer match on employee 401(k) contributions to support planning for the future.
  • Paid time off to volunteer at an organization of your choice.
  • Funding for select family-forming benefits.
  • Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

10x Genomics
Permanent
March 22, 2026

Scientist II, Clinical Bioinformatics

$123,400 — $167,000
Pleasanton, California, USA HQ
Onsite

About The Role

10x Genomics is establishing a diagnostics effort, translating our leading single-cell and spatial assay technologies into impactful clinical applications. We are seeking a Scientist II to join the clinical bioinformatics team. The ideal candidate excels at distilling complex biological questions into actionable computational strategies, implementing computational/statistical methods and applying them to large-scale single-cell or spatial transcriptomics datasets to derive clinically meaningful insights.

The role requires a biology-first mindset, proficiency with large-scale bioinformatics analyses, strong scientific acumen and statistical rigor. The successful candidate will have an opportunity to work with some of the largest biomedical datasets assayed using cutting-edge 10x Genomics technologies, deriving clinical insights that power the next generation of clinical diagnostics.

What You Will Be Doing:

  • Implement rigorous computational/statistical methods for single-cell and spatial transcriptomics data analysis.
  • Derive actionable insights from clinical/translational single-cell or in-situ spatial datasets.
  • Design, implement and validate biomarkers for diagnostic applications.
  • Implement and maintain bioinformatics pipelines for reproducible, large-scale data processing.
  • Process and analyze single-cell or in-situ spatial transcriptomics datasets spanning hundreds to thousands of samples.

To Be Successful, You Will Need:

  • Ph.D. in bioinformatics, computational biology, genomics or a related discipline with extensive hands-on experience in single-cell NGS data analysis.
  • A minimum of 2 years of industry experience post-Ph.D.
  • Experience analyzing large-scale single-cell or spatial transcriptomics datasets to derive biologically meaningful insights and/or diagnostic biomarkers.
  • In-depth understanding of the assumptions, limitations and caveats of statistical methods.
  • Experience developing and optimizing high-performance, scalable code.
  • Proficiency working in a Linux environment.
  • Goal-oriented, self-motivated and an independent problem solver.
  • Meticulous attention to detail and a conscientious work ethic.

Preferred Skills

  • Hands-on experience with 10x Genomics single-cell and in-situ transcriptomics technologies is a strong preference.
  • Hands-on research experience in cancer or autoimmune diseases is a strong preference.
  • Knowledge of clinical genomics, biomarker discovery and diagnostics.
  • Development of statistical models and algorithms for single-cell or spatial transcriptomics data.
  • Application of machine learning, particularly in the context of genomics.
  • Proficiency with workflow orchestration frameworks such as Snakemake, Nextflow or Martian.
  • Programming best practices including data analysis reproducibility, version control, design patterns, testing, debugging and profiling.
  • Track record of writing production-level code or maintaining published software packages.
  • High-throughput computing infrastructure such as HPCs or cloud computing.

Pay Range

$123,400 — $167,000 USD

Actual base pay depends on skills, qualifications, and experience. This role is also eligible for equity grants, health/retirement benefits, and annual bonus or sales incentive programs.

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us—it is a commitment. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

Fulgent
Permanent
March 22, 2026

Senior Bioinformatics Scientist I

$140,000 - $165,000
El Monte, CA
Onsite

Description

About Us

Founded in 2011, Fulgent has evolved into a premier, full-service genomic testing company built around a foundational technology platform.

Through our diverse testing menu, Fulgent is focused on transforming patient care in oncology, anatomic pathology, infectious and rare diseases, and reproductive health. We believe that by providing a wide range of effective, flexible testing options in conjunction with best-in-class service and support, we can redefine the way medicine is managed for patients and clinicians alike.

Since integrating with our therapeutic development business, Fulgent is also developing drug candidates for treating a broad range of cancers using a novel nanoencapsulation and targeted therapy platform. By merging our fields of expertise, we aim to become a fully integrated precision medicine company.

Summary of Position

As a Senior Bioinformatics Scientist, you will collaborate in cross-functional teams to design, implement and continually improve advanced computational pipelines for high-throughput analysis of multiple types of NGS data. You will work independently in refining methodologies for data analysis, processing, visualization and storage.  You will also be assigned leadership roles in projects with mentor responsibility to junior members of the team.  You will strive to maximize efficiency, quality, reliability and customer usability and satisfaction.

Key Job Elements

Research and Development

  • Investigate and refine available algorithms, methods and data sources.
  • Work independently to define, prioritize and complete objectives to meet company goals.
  • Make recommendations for pipeline component improvements, or new pipelines.
  • Write SOPs for new or updated pipeline components, or new pipelines.
  • Write specifications for implementation by software developers.
  • Oversee pipeline development and integration.

Production and Customer Support

  • Investigate and resolve analysis and pipeline production issues.
  • Review client projects for compatibility with current pipelines, make recommendations and implement customizations as needed.
  • Oversee sequencing service projects, ensuring timely processing, quality results and client satisfaction.
  • Support software and LIMS developers in automation efforts.
  • Perform specialized analyses as needed for specific projects.
  • Keep up-to-date with current best practices and emerging methods.
  • Treat data with a high level of integrity and ethics.

Data Maintenance

  • Investigate available annotation and reference data sources.
  • Validate and deploy/update selected data sources.
  • Write reports detailing validation/update methodology and results.
  • Write SOPs for updating existing or new data sources.

Validation

  • Develop appropriate procedures for testing and validation of new or updated pipelines or pipeline components.
  • Document and maintain data used for testing and validation.
  • Write validation reports detailing validation methodology and results.

Qualifications

Knowledge/Experience

  • Ph.D. degree from an accredited institution in Bioinformatics, Biostatistics or related field.
  • 5+ years of experience in a related scientific discipline (Bioinformatics preferred).
  • Demonstrated mastery of Fulgent specific methods and processes.
  • Experience analyzing multiple types of next-generation sequencing (NGS) data
  • Expertise with statistics for big data analysis and multiomics data integration.
  • Expert level hands-on skills in bioinformatics databases and tools.
  • Expert level in relevant programming languages, preferably Scala, Java, Python, and Bash.
  • Must enjoy working in a multi-disciplinary and collaborative environment.
  • Ability to troubleshoot both individually and as part of a team.
  • Excellent oral and written skills with the ability to communicate in an open, transparent, timely and consistent manner.
  • Experience in team software development and integration projects is a plus.

Supervisor Responsibilities

  • None

Reports To

  • Director, Biointegration

Environment

Fulgent Therapeutics LLC is an Equal Employment Opportunity Employer.

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable qualified individuals with disabilities to perform the essential functions. The term “qualified individual with a disability” means an individual with a disability who, with or without reasonable accommodation, can perform the essential functions of the position.

For California residents, please see the link below to access our CCPA Privacy Notice.

CCPA Privacy Notice for California Residents

https://tinyurl.com/FulgentCCPA

Please note that Fulgent (and its affiliated companies, including Inform Diagnostics and CSI Laboratories) does not accept unsolicited information and/or resumes from search firms or agencies for our job postings. Search firms or agencies without an applicable contract and/or express approval to recruit for the role in question — that choose to submit a resume or client information to our career page or to any employee of Fulgent — will not be eligible for payment of any fee(s), and any associated shared data will become the property of Fulgent.

GATC Health
Permanent
March 22, 2026

Bioinformatics Analyst

$70,000 - $85,000
Irvine, CA
Onsite

Company Overview: GATC Health is an innovative TechBio company at the forefront of revolutionizing pharmaceutical discovery and accelerating their development through the integration of artificial intelligence (AI), science and finance. Our company is dedicated to advancing therapeutic discoveries and improving human health by leveraging the power of technology and interdisciplinary collaboration.

Position Overview: We are seeking a talented Bioinformatics Analyst to join our dynamic, multi-disciplinary team that is responsible for implementing and aiding in design and analysis software and informatics pipelines for primary, secondary, and tertiary analysis of data generated from transcriptional, proteomic, and mult-omic assays. As a Bioinformatics Scientist, you will innovate, develop and implement novel analysis methods for different data types from sparse to large and complex datasets to support the internal development and validation of new pharmaceutical assets and the development of end-user, customer-facing data analysis and visualization for biotech customers and stakeholders. A highly motivated scientist with broad expertise and experience in bioinformatics, computational biology, transcriptomics, proteomics and multi-omics would be an ideal fit for this position.

Roles and Responsibilities

  • Prep and Process data through GATC platform based on customer or internal end user requirements.
  • Implement primary and secondary analysis tools for GATC’s assays.
  • Work with cross-disciplinary R&D teams to develop and implement new discovery and risk assessment product applications.
  • Aid in Development and implementation processes and algorithms for multi-modal datasets, scalable to very large numbers of samples.
  • Engage with external collaborators on the evaluation of beta version products and analysis of novel data.

Role Requirements

  • Degree in computational biology, bioinformatics, computer science or similar.
  • Experience analyzing complex multi-omic datasets, including human or single cell data.
  • Experience implementing, and evaluating novel bioinformatics algorithms and pipelines.
  • Experience in programming in scripting (Python or similar) and interpreted languages (R, etc).
  • Demonstrated ability to become proficient in new fields and work with interdisciplinary teams.
  • Excellent verbal/written communication and interpersonal skills with scientist and non-scientists.

Role Preferences

  • Experience using or interfacing with machine learning algorithms.
  • Experience analyzing and interpreting large-scale human or single cell datasets.
  • Experience with professional software development methods and tools in a team environment.
  • Experience in programming in scripting (Python), interpreted (R ) and compiled languages (C++ / Rust / Java).
  • Experience working with collaborators, including lab scientists on multi-omic method development.
  • Experience visualizing scientific datasets and results.
  • Experience using cloud computing environments.
  • Computational biology and bioinformatics innovation.

$70,000 - $85,000 a year

Why Join Us:

• Opportunity to work at the intersection of technology and science, driving innovation in pharmaceutical discovery.

• Collaborative and inclusive work culture that values diversity, creativity, and continuous learning.

• Competitive compensation package, including salary, benefits, and opportunities for professional development.

• Chance to make a meaningful impact on human health and contribute to groundbreaking research and development projects.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.