About Nautilus
At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.
We are looking for a Sr. Director of Bioinformatics to join our growing company. Being successful in our goal of delivering novel proteomic insights to the world hinges on our ability to analyze and understand large, complex, and diverse data sets that result from our experimental efforts, surfacing any key insights that might be hidden within. A candidate stepping into this highly visible role will provide both technical and people leadership for diverse bioinformatics teams and work with R&D leaders to define strategic direction. Our novel proteomic technology is in its formative stages, which means that anyone in this role will have an outsized impact on our technology and customer success.
This position will report to the SVP of Product Development and is located in San Carlos, CA (hybrid: minimum 3 days/week in office).
Responsibilities
- Team Leadership & Growth: Lead, manage, mentor, and grow several teams of bioinformaticians across a wide range of experience levels, areas of expertise, and scopes of responsibility.
- Cross-Functional Partnership: Serve as a true thought partner to experimental, engineering, and product teams—working alongside them to guide next steps, prioritize tradeoffs, and accelerate learning.
- Commercial Integration: Work with commercial and software teams to translate bioinformatics capabilities into scalable, reliable customer solutions.
- Experimental Strategy: Guide the design of individual experiments as well as shape broader experimental strategy and priorities.
- Data Delivery: Own the successful delivery of data analyses and processing solutions in both R&D and customer-facing product contexts.
- Navigating Ambiguity: Operate effectively in fast-moving, ambiguous environments by balancing risk, setting priorities, and helping teams navigate uncertainty.
- Technical Guidance: Provide hands-on technical contributions as appropriate to your teams’ strengths and gaps.
- Executive Leadership: Drive corporate strategy and initiatives, act as a positive cultural role model, and serve as an ambassador for Nautilus to the broader scientific world.
Requirements
- Experience: 15+ years of relevant experience in a high-performing biotechnology organization, including 10+ years in a leadership role.
- Education: PhD in Bioinformatics or a related field.
- Proven Leadership: Demonstrated track record of leading multiple bioinformatics teams to success on complex, highly interdisciplinary projects.
- Assay & Experimental Collaboration: Proven experience partnering with scientists developing novel biochemical approaches or assays.
- People Management: Mastery in creating and nurturing high-performing bioinformatics teams through coaching, hiring, performance reviews, technical mentorship, and modern management techniques.
- Technical Breadth: Fluency in a wide variety of statistical analysis techniques, data processing/visualization approaches, programming languages and environments, and biological experimental methods—with the ability to quickly master new domains on the fly.
- Novel Data Problem-Solving: Creative thinker capable of developing foundational approaches for extracting value from entirely novel data sets and generating actionable insights from imperfect data (missing values, batch effects, skewed distributions, outliers).
- Operational Excellence: Strong organizational, communication, problem-solving, and project management skills, with a hands-on willingness to jump in wherever needed.
- Influence & Trust: A trusted leader who can drive outcomes both directly and through cross-functional collaboration and influence.
- Travel: Ability to travel up to 20% of the time.
