Altos Labs is a mission-driven biotechnology company focused on restoring cell health and resilience through cell rejuvenation to reverse disease, injury, and disabilities. Named one of the Top 3大 Biotech Companies and ranked on the Forbes Best Startups in America list, Altos Labs brings together exceptional global scientists and industry leaders within an inclusive, collaborative culture centered on scientific excellence and belonging.
Role Overview
- Position: Scientist / Senior Scientist, Metabolomics Group Lead
- Location: Redwood City, CA
- Schedule: Onsite
- Base Compensation Ranges:
- Scientist II: $156,800 - $201,000 / year
- Senior Scientist: $172,400 - $221,000 / year
The Mass Spectrometry Hub sits within the Institute of Technology, utilizing an array of cutting-edge instrumentation. The Metabolomics Group Lead is responsible for the end-to-end management of metabolomics and lipidomics projects—spanning experimental design, sample preparation, measurement, data processing, and delivery. This role collaborates closely with scientific and bioinformatics teams to guarantee robust data generation and maintain operational excellence across liquid chromatography-mass spectrometry (LC-MS) platforms.
Responsibilities
Project Management & Collaboration
- Collaborate with cross-functional scientists to define project objectives, assess technical feasibility, and establish clear deliverables and timelines.
- Maintain accurate, up-to-date project tracking and documentation using Benchling and shared project management tools.
- Communicate project status, timelines, and potential risks effectively to internal stakeholders and leadership.
Lab Operations & Sample Processing
- Execute and supervise sample preparation workflows for steady-state metabolomics and lipidomics.
- Optimize and adapt extraction protocols to support the analysis of diverse and challenging biological samples (cells, tissues, and biofluids).
- Operate, maintain, and troubleshoot LC-MS instrumentation—including the Thermo Exploris 240, SCIEX 7500, and Vanquish HPLC—to ensure optimal performance and minimize instrument downtime.
Data Analysis & Bioinformatics
- Process and analyze raw datasets using specialized software such as Skyline and Compound Discoverer.
- Coordinate with bioinformatics teams to ensure accurate data processing, rigorous quality control (QC), and efficient project execution.
Qualifications
Minimum Requirements
- Education: PhD (or equivalent experience) in metabolomics, lipidomics, analytical chemistry, biochemistry, or a related discipline.
- Mass Spectrometry Expertise: More than 6 years of hands-on experience with both High-Resolution Accurate Mass (HRAM) and Low-Resolution Mass Spectrometry (LRMS) platforms. Preferred experience specifically includes Orbitrap Exploris and SCIEX triple quadrupole mass spectrometry platforms.
- Experimental Design: Strong experimental design and problem-solving skills, with direct experience performing sample preparation on cells, tissues, and biofluids.
- Leadership & Mentorship: Demonstrated experience mentoring team members and managing collaborative projects with scientists from diverse training backgrounds.
Preferred Attributes (Ideal candidates satisfy 2 or more)
- Experience developing completely new methods for the analysis of metabolites or lipids of interest.
- Prior experience in Metabolite Identification (MetID) and trapping within the context of drug metabolism.
- Experience executing large-scale discovery studies exceeding 1,000 samples.
- Experience designing and interpreting complex isotope tracing experiments (e.g., metabolic flux analysis).
- Experience integrating metabolomics/lipidomics datasets with other multi-omics modalities, such as proteomics and transcriptomics.
Company Culture & Protections
Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.
Equal Opportunity Employer
Altos Labs provides equal employment opportunities to all employees and applicants without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by law.
Candidate Security & Scam Notice
Altos Labs will never ask you to download a third-party messaging app for an interview, nor will they require an outlay of your own money to begin employment. If you experience an interaction matching this description from individuals claiming to represent the company, it is a fraudulent job scam.
